日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification of novel small molecule chaperone activators for neurodegenerative disease treatment.

鉴定用于治疗神经退行性疾病的新型小分子分子伴侣激活剂

期刊:Biomedicine & Pharmacotherapy
影响因子:7.5
doi:10.1016/j.biopha.2025.118049
Ho Anita K, Jeganathan Fiona, Bictash Magda, Chen Han-Jou
神经科学
发表日期：2025
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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

C9orf72 poly GA RAN翻译蛋白通过聚集和毒性在肌萎缩侧索硬化症中发挥关键作用

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddaa181
Lee, Youn-Bok; Baskaran, Pranetha; Gomez-Deza, Jorge; Chen, Han-Jou; Nishimura, Agnes L; Smith, Bradley N; Troakes, Claire; Adachi, Yoshitsugu; Stepto, Alan; Petrucelli, Leonard; Gallo, Jean-Marc; Hirth, Frank; Rogelj, Boris; Guthrie, Sarah; Shaw, Christopher E
RAN
毒理研究
发表日期：2021
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RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

RRM邻近的TARDBP突变会破坏RNA结合并加剧TDP-43蛋白病。

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awz313
Chen, Han-Jou; Topp, Simon D; Hui, Ho Sang; Zacco, Elsa; Katarya, Malvika; McLoughlin, Conor; King, Andrew; Smith, Bradley N; Troakes, Claire; Pastore, Annalisa; Shaw, Christopher E
DBP
发表日期：2019
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ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function

ALS 相关的错义和无义 TBK1 突变均可导致激酶功能丧失

期刊:Neurobiology of Aging
影响因子:3.7
doi:10.1016/j.neurobiolaging.2018.06.015
Martina de Majo, Simon D Topp, Bradley N Smith, Agnes L Nishimura, Han-Jou Chen, Athina Soragia Gkazi, Jack Miller, Chun Hao Wong, Caroline Vance, Frank Baas, Anneloor L M A Ten Asbroek, Kevin P Kenna, Nicola Ticozzi, Alberto Garcia Redondo, Jesús Esteban-Pérez, Cinzia Tiloca, Federico Verde, Stefan
信号转导
发表日期：2018
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Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

囊泡运输蛋白膜联蛋白 A11 的突变与肌萎缩侧索硬化症有关

期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.aad9157
Bradley N Smith, Simon D Topp, Claudia Fallini, Hideki Shibata, Han-Jou Chen, Claire Troakes, Andrew King, Nicola Ticozzi, Kevin P Kenna, Athina Soragia-Gkazi, Jack W Miller, Akane Sato, Diana Marques Dias, Maryangel Jeon, Caroline Vance, Chun Hao Wong, Martina de Majo, Wejdan Kattuah, Jacqueline C
免疫
神经
多发性硬化症
FCM
IF
IHC-P
GFP
发表日期：2017
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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

C9orf72 聚 GA RAN 翻译蛋白通过聚集和毒性在肌萎缩侧索硬化症中起关键作用

期刊:Human Molecular Genetics
影响因子:3.1
doi:10.1093/hmg/ddx350
Youn-Bok Lee, Pranetha Baskaran, Jorge Gomez-Deza, Han-Jou Chen, Agnes L Nishimura, Bradley N Smith, Claire Troakes, Yoshitsugu Adachi, Alan Stepto, Leonard Petrucelli, Jean-Marc Gallo, Frank Hirth, Boris Rogelj, Sarah Guthrie, Christopher E Shaw
RAN
毒理研究
发表日期：2017
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Reply: The role of DNAJB2 in amyotrophic lateral sclerosis

回复：DNAJB2在肌萎缩侧索硬化症中的作用

期刊:Brain
影响因子:11.7
doi:10.1093/brain/aww155
Chen, Han-Jou; Shaw, Christopher E
发表日期：2016
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The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis

热休克反应在TDP-43清除中起着重要作用：肌萎缩侧索硬化症中功能障碍的证据

期刊:Brain
影响因子:11.7
doi:10.1093/brain/aww028
Chen, Han-Jou; Mitchell, Jacqueline C; Novoselov, Sergey; Miller, Jack; Nishimura, Agnes L; Scotter, Emma L; Vance, Caroline A; Cheetham, Michael E; Shaw, Christopher E
发表日期：2016
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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

TDP-43蛋白病与肌萎缩侧索硬化症：疾病机制和治疗靶点的深入研究

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1007/s13311-015-0338-x
Scotter, Emma L; Chen, Han-Jou; Shaw, Christopher E
发表日期：2015
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Erratum to: TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

勘误：TDP-43蛋白病与ALS：疾病机制和治疗靶点的见解

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1007/s13311-015-0351-0
Scotter, Emma L; Chen, Han-Jou; Shaw, Christopher E
ALS
发表日期：2015
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