日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Author Correction: Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

作者更正:对一种与磷脂酰肌醇3-激酶p110α的RAS结合域结合的环状肽进行表征

Ismail, Mohamed; Martin, Stephen R; George, Roger; Houghton, Francesca; Kelly, Geoff; Chaleil, Raphaël A G; Anastasiou, Panayiotis; Wang, Xinyue; O'Reilly, Nicola; Federico, Stefania; Joshi, Dhira; Nagaraj, Hemavathi; Cooley, Rachel; Hui, Ning Sze; Molina-Arcas, Miriam; Hancock, David C; Tavassoli, Ali; Downward, Julian

RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma.

RAS致癌活性可预测肺腺癌对化疗的反应和预后

East Philip, Kelly Gavin P, Biswas Dhruva, Marani Michela, Hancock David C, Creasy Todd, Sachsenmeier Kris, Swanton Charles, Downward Julian, de Carné Trécesson Sophie

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

开发联合疗法以最大限度地发挥KRAS-G12C抑制剂在肺癌治疗中的疗效

Molina-Arcas, Miriam; Moore, Christopher; Rana, Sareena; van Maldegem, Febe; Mugarza, Edurne; Romero-Clavijo, Pablo; Herbert, Eleanor; Horswell, Stuart; Li, Lian-Sheng; Janes, Matthew R; Hancock, David C; Downward, Julian

Coordinate direct input of both KRAS and IGF1 receptor to activation of PI3 kinase in KRAS-mutant lung cancer

在KRAS突变型肺癌中,KRAS和IGF1受体协同直接输入激活PI3激酶。

Molina-Arcas, Miriam; Hancock, David C; Sheridan, Clare; Kumar, Madhu S; Downward, Julian

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies

对KRAS癌基因依赖性癌细胞中合成致死相互作用的测定揭示了新的治疗靶向策略

Steckel, Michael; Molina-Arcas, Miriam; Weigelt, Britta; Marani, Michaela; Warne, Patricia H; Kuznetsov, Hanna; Kelly, Gavin; Saunders, Becky; Howell, Michael; Downward, Julian; Hancock, David C