日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Aβ degradation pathway.

内皮素转化酶 1 的特性分析表明，它是多酶 Aβ 降解途径中的关键酶。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2507450122
Ulku Irem, Ansari Fatima El, Hancock Mark A, Zhou Hedi, Cagnone Gael, Joyal Jean-Sebastien, Fisher Teddy A J, Kennedy Timothy E, Liebsch Filip, Multhaup Gerhard
发表日期：2025
文献求助 收藏

Assembly of the Tn7 targeting complex by a regulated stepwise process.

通过受控的逐步过程组装 Tn7 靶向复合物

期刊:Molecular Cell
影响因子:16.6
doi:10.1016/j.molcel.2024.05.012
Shen Yao, Krishnan Shreya S, Petassi Michael T, Hancock Mark A, Peters Joseph E, Guarné Alba
其它
发表日期：2024
文献求助 收藏

Structural basis for allosteric PARP-1 retention on DNA breaks

DNA断裂处PARP-1变构保留的结构基础

期刊:Science
影响因子:45.8
doi:10.1126/science.aax6367
Zandarashvili, Levani; Langelier, Marie-France; Velagapudi, Uday Kiran; Hancock, Mark A; Steffen, Jamin D; Billur, Ramya; Hannan, Zain M; Wicks, Andrew J; Krastev, Dragomir B; Pettitt, Stephen J; Lord, Christopher J; Talele, Tanaji T; Pascal, John M; Black, Ben E
PARP
发表日期：2020
文献求助 收藏

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity

合成的重氮酰胺DZ-2384对微管曲率和动力学有显著影响，且无神经毒性。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aag1093
Wieczorek, Michal; Tcherkezian, Joseph; Bernier, Cynthia; Prota, Andrea E; Chaaban, Sami; Rolland, Yannève; Godbout, Claude; Hancock, Mark A; Arezzo, Joseph C; Ocal, Ozhan; Rocha, Cecilia; Olieric, Natacha; Hall, Anita; Ding, Hui; Bramoullé, Alexandre; Annis, Matthew G; Zogopoulos, George; Harran, Patrick G; Wilkie, Thomas M; Brekken, Rolf A; Siegel, Peter M; Steinmetz, Michel O; Shore, Gordon C; Brouhard, Gary J; Roulston, Anne
毒理研究
发表日期：2016
文献求助 收藏

Aβ42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-β42 species and protects synaptic structure and function

Aβ42寡聚体相互作用肽（AIP）可中和有毒的淀粉样蛋白β42，从而保护突触结构和功能。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep15410
Barucker, Christian; Bittner, Heiko J; Chang, Philip K-Y; Cameron, Scott; Hancock, Mark A; Liebsch, Filip; Hossain, Shireen; Harmeier, Anja; Shaw, Hunter; Charron, François M; Gensler, Manuel; Dembny, Paul; Zhuang, Wei; Schmitz, Dietmar; Rabe, Jürgen P; Rao, Yong; Lurz, Rudi; Hildebrand, Peter W; McKinney, R Anne; Multhaup, Gerhard
AIP
神经科学
发表日期：2015
文献求助 收藏