日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution

通过赖氨酸到精氨酸(KR)的整体取代系统性地提高蛋白质结晶效率

Banayan, Nooriel E; Loughlin, Blaine J; Singh, Shikha; Forouhar, Farhad; Lu, Guanqi; Wong, Kam-Ho; Neky, Matthew; Hunt, Henry S; Bateman, Larry B Jr; Tamez, Angel; Handelman, Samuel K; Price, W Nicholson; Hunt, John F

Author Correction: Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

作者更正:全基因组关联研究表明血清肝酶与多种代谢和肝脏病理有关

Chen, Vincent L; Du, Xiaomeng; Chen, Yanhua; Kuppa, Annapurna; Handelman, Samuel K; Vohnoutka, Rishel B; Peyser, Patricia A; Palmer, Nicholette D; Bielak, Lawrence F; Halligan, Brian; Speliotes, Elizabeth K

A new framework for host-pathogen interaction research

宿主-病原体相互作用研究的新框架

Yu, Hong; Li, Li; Huffman, Anthony; Beverley, John; Hur, Junguk; Merrell, Eric; Huang, Hsin-Hui; Wang, Yang; Liu, Yingtong; Ong, Edison; Cheng, Liang; Zeng, Tao; Zhang, Jingsong; Li, Pengpai; Liu, Zhiping; Wang, Zhigang; Zhang, Xiangyan; Ye, Xianwei; Handelman, Samuel K; Sexton, Jonathan; Eaton, Kathryn; Higgins, Gerry; Omenn, Gilbert S; Athey, Brian; Smith, Barry; Chen, Luonan; He, Yongqun

Population-based meta-analysis and gene-set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids

基于人群的荟萃分析和基因集富集分析表明,FXR/RXR通路是脂肪肝疾病和血脂异常的共同特征。

Handelman, Samuel K; Puentes, Yindra M; Kuppa, Annapurna; Chen, Yanhua; Du, Xiaomeng; Feitosa, Mary F; Palmer, Nicholette D; Speliotes, Elizabeth K

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

全基因组关联研究表明,血清肝酶与多种代谢和肝脏病理有关。

Chen, Vincent L; Du, Xiaomeng; Chen, Yanhua; Kuppa, Annapurna; Handelman, Samuel K; Vohnoutka, Rishel B; Peyser, Patricia A; Palmer, Nicholette D; Bielak, Lawrence F; Halligan, Brian; Speliotes, Elizabeth K

BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program.

BET溴结构域抑制剂阻断了AR抑制、E2F1激活的治疗后出现的神经内分泌前列腺癌谱系可塑性程序

Kim Dae-Hwan, Sun Duanchen, Storck William K, Welker Leng Katherine, Jenkins Chelsea, Coleman Daniel J, Sampson David, Guan Xiangnan, Kumaraswamy Anbarasu, Rodansky Eva S, Urrutia Joshua A, Schwartzman Jacob A, Zhang Chao, Beltran Himisha, Labrecque Mark P, Morrissey Colm, Lucas Jared M, Coleman Ilsa M, Nelson Peter S, Corey Eva, Handelman Samuel K, Sexton Jonathan Z, Aggarwal Rahul, Abida Wassim, Feng Felix Y, Small Eric J, Spratt Daniel E, Bankhead Armand 3rd, Rao Arvind, Gesner Emily M, Attwell Sarah, Lakhotia Sanjay, Campeau Eric, Yates Joel A, Xia Zheng, Alumkal Joshi J

A Meta-Analysis of the Transferability of Bone Mineral Density Genetic Loci Associations From European to African Ancestry Populations

骨矿物质密度遗传位点关联性从欧洲血统人群到非洲血统人群可转移性的荟萃分析

Yau, Michelle S; Kuipers, Allison L; Price, Ryan; Nicolas, Aude; Tajuddin, Salman M; Handelman, Samuel K; Arbeeva, Liubov; Chesi, Alessandra; Hsu, Yi-Hsiang; Liu, Ching-Ti; Karasik, David; Zemel, Babette S; Grant, Struan Fa; Jordan, Joanne M; Jackson, Rebecca D; Evans, Michele K; Harris, Tamara B; Zmuda, Joseph M; Kiel, Douglas P

Loci identified by a genome-wide association study of carotid artery stenosis in the eMERGE network

eMERGE网络中通过全基因组关联研究鉴定的颈动脉狭窄位点

Palmer, Melody R; Kim, Daniel S; Crosslin, David R; Stanaway, Ian B; Rosenthal, Elisabeth A; Carrell, David S; Cronkite, David J; Gordon, Adam; Du, Xiaomeng; Li, Yatong K; Williams, Marc S; Weng, Chunhua; Feng, Qiping; Li, Rongling; Pendergrass, Sarah A; Hakonarson, Hakon; Fasel, David; Sohn, Sunghwan; Sleiman, Patrick; Handelman, Samuel K; Speliotes, Elizabeth; Kullo, Iftikhar J; Larson, Eric B; Jarvik, Gail P

Genetic variants that associate with cirrhosis have pleiotropic effects on human traits

与肝硬化相关的基因变异对人类性状具有多效性影响

Chen, Vincent L; Chen, Yanhua; Du, Xiaomeng; Handelman, Samuel K; Speliotes, Elizabeth K

Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibition

通过抑制DNA损伤修复来减轻胶质母细胞瘤的替莫唑胺耐药性

Sorribes, Inmaculada C; Handelman, Samuel K; Jain, Harsh V