日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural and functional studies of the EGF20-27 region reveal new features of the human Notch receptor important for optimal activation

对 EGF20-27 区域的结构和功能研究揭示了人类 Notch 受体的新特征,这些特征对于其最佳激活至关重要。

Bo, Zhihan; Rowntree, Thomas; Johnson, Steven; Nurmahdi, Hilman; Suckling, Richard J; Hill, Johan; Korona, Boguslawa; Weisshuhn, Philip C; Sheppard, Devon; Meng, Yao; Liang, Shaoyan; Lowe, Edward D; Lea, Susan M; Redfield, Christina; Handford, Penny A

Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer Therapy.

开发用于癌症治疗的抗JAGGED1治疗性抗体

Masiero Massimo, Li Demin, Whiteman Pat, Bentley Carol, Greig Jenny, Hassanali Tasneem, Watts Sarah, Stribbling Stephen, Yates Jenna, Bealing Ellen, Li Ji-Liang, Chillakuri Chandramouli, Sheppard Devon, Serres Sébastien, Sarmiento-Soto Manuel, Larkin James, Sibson Nicola R, Handford Penny A, Harris Adrian L, Banham Alison H

A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion

纤维蛋白-1中的一种疾病相关突变会差异性地调节整合素介导的细胞黏附。

Del Cid, Joselyn S; Reed, Nilgun Isik; Molnar, Kathleen; Liu, Sean; Dang, Bobo; Jensen, Sacha A; DeGrado, William; Handford, Penny A; Sheppard, Dean; Sundaram, Aparna B

Somatic mutant clones colonize the human esophagus with age

随着年龄增长,体细胞突变克隆会在人类食道内定植。

Martincorena, Iñigo; Fowler, Joanna C; Wabik, Agnieszka; Lawson, Andrew R J; Abascal, Federico; Hall, Michael W J; Cagan, Alex; Murai, Kasumi; Mahbubani, Krishnaa; Stratton, Michael R; Fitzgerald, Rebecca C; Handford, Penny A; Campbell, Peter J; Saeb-Parsy, Kourosh; Jones, Philip H

¹H, ¹³C and ¹⁵N assignments of the four N-terminal domains of human fibrillin-1

人纤连蛋白-1四个N端结构域的¹H、¹³C和¹⁵N元素归属

Yadin, David A; Robertson, Ian B; Jensen, Sacha A; Handford, Penny A; Redfield, Christina

¹H, ¹³C and ¹⁵N resonance assignments for the fibrillin-1 EGF2-EGF3-hybrid1-cbEGF1 four-domain fragment

纤维蛋白-1 EGF2-EGF3-hybrid1-cbEGF1 四结构域片段的¹H、¹³C 和¹⁵N 共振归属

Robertson, Ian B; Osuch, Isabelle; Yadin, David A; Handford, Penny A; Jensen, Sacha A; Redfield, Christina

Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor

Notch受体识别Jagged-1/Serrate配体的分子基础

Whiteman, Pat; de Madrid, Beatriz Hernandez; Taylor, Paul; Li, Demin; Heslop, Rebecca; Viticheep, Nattnee; Tan, Joyce Zi; Shimizu, Hideyuki; Callaghan, Juliana; Masiero, Massimo; Li, Ji Liang; Banham, Alison H; Harris, Adrian L; Lea, Susan M; Redfield, Christina; Baron, Martin; Handford, Penny A

Notch receptor-ligand binding and activation: insights from molecular studies

Notch受体-配体结合和激活:来自分子研究的见解

Chillakuri, Chandramouli R; Sheppard, Devon; Lea, Susan M; Handford, Penny A

Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc.

人类椎间盘和牛尾椎间盘中的微纤维、弹性蛋白纤维和胶原纤维

Yu Jing, Tirlapur Uday, Fairbank Jeremy, Handford Penny, Roberts Sally, Winlove C Peter, Cui Zhanfeng, Urban Jill