日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications

人工智能辅助蛋白质设计，可快速将抗体序列转化为靶向多种肽段和组蛋白修饰的胞内抗体

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adx8352.
Gabriel Galindo,Daiki Maejima,Jacob DeRoo,Scott R Burlingham,Gretchen Fixen,Tatsuya Morisaki,Hallie P Febvre,Ryan Hasbrook,Ning Zhao,Soham Ghosh,E Handly Mayton,Christopher D Snow,Brian J Geiss,Yasuyuki Ohkawa,Yuko Sato,Hiroshi Kimura,Timothy J Stasevich
表观遗传
组蛋白修饰
发表日期：2026
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Magnetic bead-based electrochemical surrogate virus neutralization test for quantification of antibody neutralizing efficiency

基于磁珠的电化学替代病毒中和试验用于定量抗体中和效率

期刊:Biosensors & Bioelectronics
影响因子:10.7
doi:10.1016/j.bios.2025.117640
Rae A Bellows ,Kira L Rahn ,Wyatt C Hummel ,E Handly Mayton ,Henri W Berry ,Elizabeth P Ryan ,Brian J Geiss ,David S Dandy ,Charles S Henry
微生物学
发表日期：2025
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AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications

人工智能辅助蛋白质设计，可快速将抗体序列转化为靶向多种肽段和组蛋白修饰的胞内抗体

期刊:
影响因子:
doi:10.1101/2025.02.06.636921
Galindo, Gabriel; Maejima, Daiki; DeRoo, Jacob; Burlingham, Scott R; Fixen, Gretchen; Morisaki, Tatsuya; Febvre, Hallie P; Hasbrook, Ryan; Zhao, Ning; Ghosh, Soham; Mayton, E Handly; Snow, Christopher D; Geiss, Brian J; Ohkawa, Yasuyuki; Sato, Yuko; Kimura, Hiroshi; Stasevich, Timothy J
表观遗传
组蛋白修饰
发表日期：2025
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An RNA damage response network mediates the lethality of 5-FU in colorectal cancer

RNA 损伤反应网络介导 5-FU 在结直肠癌中的致死率

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2024.101778
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D Handly, Jesse C Patterson, Ian G Cannell, Lucia Suarez-Lopez, Aaron M Hosios, Anh Dinh, Donald S Kirkpatrick, Kebing Yu, Christopher M Rose, Jonathan M Hernandez, Haeun Hwangbo, Adam C Palmer, Matthew G Vander H
肿瘤
肠癌
Human
H2AX
发表日期：2024
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Preclinical Efficacy of the Antibody-Drug Conjugate CLDN6-23-ADC for the Treatment of CLDN6-Positive Solid Tumors

抗体药物偶联物CLDN6-23-ADC治疗CLDN6阳性实体瘤的临床前疗效

期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-22-2981
Martina S J McDermott ，Neil A O'Brien ，Benjamin Hoffstrom ，KeWei Gong ，Ming Lu ，Jun Zhang ，Tong Luo ，Min Liang ，Weiping Jia ，Jenny J Hong ，Kevin Chau ，Simon Davenport ，Bin Xie ，Michael F Press ，Richard Panayiotou ，Abram Handly-Santana ，Joan S Brugge ，Leonard Presta ，John Glaspy ，Dennis J Slamon
发表日期：2023
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An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types

RNA 损伤反应网络介导 5-FU 在临床相关肿瘤类型中的致死率

期刊:
影响因子:
doi:10.1101/2023.04.28.538590
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D Handly, Jesse C Patterson, Ian G Cannell, Lucia Suarez-Lopez, Aaron M Hosios, Anh Dinh, Donald S Kirkpatrick, Kebing Yu, Christopher M Rose, Jonathan M Hernandez, Haeun Hwangbo, Adam C Palmer, Matthew G Vander H
信号转导
肿瘤
发表日期：2023
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Sex-Specific Evaluation of Arterial Stiffness and Left Ventricular Remodeling: Can We Rely on Dimensionless Ratios?

性别特异性动脉硬化和左心室重塑评估：我们可以依赖无量纲比率吗？

期刊:JACC Advances
影响因子:
doi:10.1016/j.jacadv.2023.100431
Kerkhof, Peter L M; Antohi, Elena-Laura; Handly, Neal
动脉粥样硬化
发表日期：2023
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Synergistic combination therapy delivered via layer-by-layer nanoparticles induces solid tumor regression of ovarian cancer

通过逐层纳米粒子递送的协同联合疗法诱导卵巢癌实体肿瘤消退

期刊:Bioengineering & Translational Medicine
影响因子:6.1
doi:10.1002/btm2.10429
Stephanie Kong, Pearl Moharil, Abram Handly-Santana, Natalie Boehnke, Richard Panayiotou, Victoria Gomerdinger, Gil Covarrubias, Ivan S Pires, Ioannis Zervantonakis, Joan Brugge, Paula T Hammond
肿瘤
卵巢癌
发表日期：2022
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Dynamic Perfluorinated Gas MRI Shows Improved Lung Ventilation in People with Cystic Fibrosis after Elexacaftor/Tezacaftor/Ivacaftor: An Observational Study

动态全氟化气体磁共振成像显示，服用Elexacaftor/Tezacaftor/Ivacaftor后囊性纤维化患者的肺通气功能得到改善：一项观察性研究

期刊:Journal of Clinical Medicine
影响因子:2.9
doi:10.3390/jcm11206160
Goralski, Jennifer L; Chung, Sang Hun; Ceppe, Agathe S; Powell, Margret Z; Sakthivel, Muthu; Handly, Brian D; Lee, Yueh Z; Donaldson, Scott H
发表日期：2022
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Toxoplasmosis Outbreak Associated With Toxoplasma gondii-Contaminated Venison-High Attack Rate, Unusual Clinical Presentation, and Atypical Genotype

与弓形虫污染鹿肉相关的弓形虫病暴发——高发病率、不寻常的临床表现和非典型基因型

期刊:Clinical Infectious Diseases
影响因子:7.3
doi:10.1093/cid/ciaa285
Schumacher, Amy C; Elbadawi, Lina I; DeSalvo, Traci; Straily, Anne; Ajzenberg, Daniel; Letzer, David; Moldenhauer, Ellen; Handly, Tammy L; Hill, Dolores; Dardé, Marie-Laure; Pomares, Christelle; Passebosc-Faure, Karine; Bisgard, Kristine; Gomez, Carlos A; Press, Cindy; Smiley, Stephanie; Montoya, José G; Kazmierczak, James J
微生物学
弓形虫病
发表日期：2021
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