日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos

结合SNP亲本单倍型分析和强度分析，可以识别植入前人类胚胎中的减数分裂和有丝分裂非整倍体以及常见的节段性非整倍体。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-21029-y
Handyside, Alan H; Newnham, Louise; Newnham, Matthew; Henning, Dominika; Velebny, Jan; Pozdena, Jan; Krmelova, Jindriska; Horak, Jakub
发表日期：2025
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Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model

脑室内注射改良的己糖胺酶可改善 GM2 小鼠模型中的晚期神经退行性病变

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0315005
Manuel E Lopez, Daniel Wendt, Roger Lawrence, Kerui Gong, Hoonsan Ong, Bryan Yip, Joseph Chen, Linley Mangini, Britta Handyside, Alexander Giaramita, Aashish Lamichhane, Melanie Lo, Vishal Agrawal, Jeremy Van Vleet, Amanda Abolhesn, Jessica B Felix, Isaac Villalpando, Vikas Bhat, Rolando De Angelis,
神经
Donkey
IgG
发表日期：2025
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Prophylactic Prednisolone Promotes AAV5 Hepatocyte Transduction Through the Novel Mechanism of AAV5 Coreceptor Platelet-Derived Growth Factor Receptor Alpha Upregulation and Innate Immune Suppression

预防性泼尼松龙通过 AAV5 辅助受体血小板衍生生长因子受体 α 上调和先天免疫抑制的新机制促进 AAV5 肝细胞转导

期刊:Human Gene Therapy
影响因子:3.9
doi:10.1089/hum.2023.065
Britta Handyside, Lening Zhang, Bridget Yates, Lin Xie, Ashrafali Mohamed Ismail, Ryan Murphy, Brian Baridon, Cheng Su, Taren Bouwman, Linley Mangini, Jorden Tahquechi, Sandra Salcido, Wesley C Minto, William T Keenan, Ioanna Ntai, Choong-Ryoul Sihn, Sherry Bullens, Stuart Bunting, Sylvia Fong
免疫
血小板
发表日期：2024
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Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos

减数分裂和有丝分裂非整倍体导致体外受精的人类植入前胚胎发育停滞

期刊:Genome Medicine
影响因子:11.2
doi:10.1186/s13073-023-01231-1
McCoy, Rajiv C; Summers, Michael C; McCollin, Abeo; Ottolini, Christian S; Ahuja, Kamal; Handyside, Alan H
发育与干细胞
发表日期：2023
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Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes

在牛卵母细胞体外成熟过程中去除复杂蛋白质并添加褪黑激素对发育、细胞遗传学和表观遗传学的影响

期刊:Frontiers in Endocrinology
影响因子:
doi:10.3389/fendo.2023.1280847
Desmond A R Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Giuseppe Silvestri, Carla Canedo-Ribeiro, Alan H Handyside, Remi Labrecque, Marc-André Sirard, Richard D Emes, Darren K Griffin, Kevin D Sinclair
表观遗传
其它细胞
发表日期：2023
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Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells

载体基因组丢失和表观遗传修饰导致哺乳动物和昆虫细胞中产生的 AAV5 载体转基因表达下降

期刊:Molecular Therapy
影响因子:12.1
doi:10.1016/j.ymthe.2022.11.001
Britta Handyside, Ashrafali Mohamed Ismail, Lening Zhang, Bridget Yates, Lin Xie, Choong-Ryoul Sihn, Ryan Murphy, Taren Bouwman, Chan Kyu Kim, Rolando De Angelis, Omair A Karim, Nicole L McIntosh, Michael Xavier Doss, Shilpa Shroff, Erno Pungor, Vikas S Bhat, Sherry Bullens, Stuart Bunting, Sylvia F
细胞生物学
其它细胞
发表日期：2022
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Application of in-vitro-cultured primary hepatocytes to evaluate species translatability and AAV transduction mechanisms of action.

应用体外培养的原代肝细胞评估物种转化性和 AAV 转导作用机制

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2022.05.008
Liu Su, Razon Lisa, Ritchie Olivia, Sihn Choong-Ryoul, Handyside Britta, Berguig Geoffrey, Woloszynek Jill, Zhang Lening, Batty Paul, Lillicrap David, Agrawal Vishal, Cortesio Christa, Gebretsadik Kahsay, Akeefe Hassibullah, Colosi Peter, Kim Benjamin, Bunting Stuart, Fong Sylvia
细胞生物学
发表日期：2022
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Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction

在粘多糖贮积症 IIIA 小鼠脑室内注射 N-磺基葡萄糖胺磺基水解酶可降低脑溶酶体功能障碍标志物

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2022.102625
Jenna Magat, Samantha Jones, Brian Baridon, Vishal Agrawal, Hio Wong, Alexander Giaramita, Linley Mangini, Britta Handyside, Catherine Vitelli, Monica Parker, Natasha Yeung, Yu Zhou, Erno Pungor, Ilya Slabodkin, Olivia Gorostiza, Allora Aguilera, Melanie J Lo, Saida Alcozie, Terri M Christianson, Pa
信号转导
发表日期：2022
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Young mice administered adult doses of AAV5-hFVIII-SQ achieve therapeutic factor VIII expression into adulthood

接受成人剂量 AAV5-hFVIII-SQ 治疗的幼鼠在成年后仍能表达治疗性因子 VIII

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:
doi:10.1016/j.omtm.2022.08.002
Lening Zhang, Bridget Yates, Ryan Murphy, Su Liu, Lin Xie, Britta Handyside, Choong-Ryoul Sihn, Taren Bouwman, Nicole Galicia, Danielle Tan, Carlos Fonck, Jeremy Arens, Annie Clark, Weiming Zhang, Sundeep Chandra, Jaydeep Srimani, Jennifer Holcomb, Andrea Van Tuyl, Joshua Henshaw, Christian Vetterma
信号转导
发表日期：2022
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Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages

对牛胚泡的分析表明，卵巢刺激不会导致染色体错误，也不会导致内细胞团和滋养外胚层谱系之间的不一致。

期刊:Theriogenology
影响因子:2.5
doi:10.1016/j.theriogenology.2020.11.021
Tutt, D A R; Silvestri, G; Serrano-Albal, M; Simmons, R J; Kwong, W Y; Guven-Ates, G; Canedo-Ribeiro, C; Labrecque, R; Blondin, P; Handyside, A H; Griffin, D K; Sinclair, K D
细胞生物学
发表日期：2021
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