High-dose treatment of cathepsin B-activatable doxorubicin prodrug nanoparticles that induce tumor-specific immunogenic cell death for immunotherapy of melanoma with minimal systemic toxicity.
高剂量治疗组织蛋白酶 B 激活的阿霉素前药纳米颗粒可诱导肿瘤特异性免疫原性细胞死亡，用于黑色素瘤的免疫治疗，且全身毒性最小。
期刊:Asian Journal of Pharmaceutical Sciences
影响因子:11.9
doi:10.1016/j.ajps.2026.101123
Oh Yoojeong, Kim Jinseong, Shim Nayeon, Yoo Hyeonji, Lee Hoyeon, Jeong Yumin, Goo Jagyeong, Lee Jeongyeon, Jo Mihee, Cho Hanhee, Kim Kwangmeyung
黑色素瘤
肿瘤
肿瘤免疫
细胞生物学
毒理研究
免疫/内分泌
