日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Directed evolution on compact landing pads yields highly efficient recombinases for large DNA integration

在紧凑型着陆平台上进行的定向进化可产生用于大片段DNA整合的高效重组酶。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1444
Kim, Hanseop; Kang, Hyo-Gu; Oh, Yeounsun; Lee, Wi-Jae; Lee, Youngjeon; Kim, Eun-Kyoung; Nam, Ki-Hoan; Lee, Dong-Seok; Lee, Seung Hwan; Sim, Bo-Woong
发表日期：2026
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Precise progerin targeting using RfxCas13d: A therapeutic avenue for Hutchinson-Gilford progeria syndrome

利用 RfxCas13d 精准靶向早衰蛋白：治疗哈钦森-吉尔福德早衰综合征的新途径

期刊:Molecular Therapy
影响因子:12.1
doi:10.1016/j.ymthe.2025.06.017
Unbin Chae ,Hae-Jun Yang ,Hanseop Kim ,Seung Hwan Lee ,Dong Gil Lee ,Jeong Young Koo ,Seung-Min Ha ,Seo-Jong Bak ,Mina Joo ,Hyun Hee Nam ,Kyung-Seob Lim ,Philyong Kang ,Hee-Chang Son ,You Jeong An ,Young-Hyun Kim ,In-Sung Song ,Sang-Hee Lee ,Hae Rim Kim ,Sang-Mi Cho ,Eun-Kyoung Kim ,Ki-Hoan Nam ,Kyung-Sook Chung ,Jae-Yoon Kim ,Seon-Yeop Kim ,Seon-Kyu Kim ,Seon-Young Kim ,Dong-Seok Lee ,Jin-Man Kim ,Young-Ho Park ,Sun-Uk Kim
发表日期：2025
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Expansion of the prime editing modality with Cas9 from Francisella novicida

利用来自弗朗西斯菌（Francisella novicida）的Cas9扩展主要编辑模式

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-022-02644-8
Oh, Yeounsun; Lee, Wi-Jae; Hur, Junho K; Song, Woo Jeung; Lee, Youngjeon; Kim, Hanseop; Gwon, Lee Wha; Kim, Young-Hyun; Park, Young-Ho; Kim, Chan Hyoung; Lim, Kyung-Seob; Song, Bong-Seok; Huh, Jae-Won; Kim, Sun-Uk; Jun, Bong-Hyun; Jung, Cheulhee; Lee, Seung Hwan
发表日期：2022
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Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system

利用增强型 CRISPR-Cas12a 系统进行高度特异性的嵌合 DNA-RNA 引导基因组编辑

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.5
doi:10.1016/j.omtn.2022.03.021
Hanseop Kim, Wi-Jae Lee, Chan Hyoung Kim, Yeounsun Oh, Lee Wha Gwon, Hyomin Lee, Woojeung Song, Junho K Hur, Kyung-Seob Lim, Kang Jin Jeong, Ki-Hoan Nam, Young-Suk Won, Kyeong-Ryoon Lee, Youngjeon Lee, Young-Hyun Kim, Jae-Won Huh, Bong-Hyun Jun, Dong-Seok Lee, Seung Hwan Lee4
发表日期：2022
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Author Correction: Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment

作者更正：基于预测的高灵敏度 CRISPR 脱靶验证采用靶向特异性 DNA 富集技术

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-020-20559-5
Kang, Seung-Hun; Lee, Wi-Jae; An, Ju-Hyun; Lee, Jong-Hee; Kim, Young-Hyun; Kim, Hanseop; Oh, Yeounsun; Park, Young-Ho; Jin, Yeung Bae; Jun, Bong-Hyun; Hur, Junho K; Kim, Sun-Uk; Lee, Seung Hwan
发表日期：2021
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Peroxiredoxin-6 regulates p38-mediated epithelial-mesenchymal transition in HCT116 colon cancer cells

过氧化物酶-6调控HCT116结肠癌细胞中p38介导的上皮-间质转化

期刊:
影响因子:
doi:10.1186/s40709-021-00153-6
Chae, Unbin; Kim, Bokyung; Kim, HanSeop; Park, Young-Ho; Lee, Seung Hwan; Kim, Sun-Uk; Lee, Dong-Seok
肿瘤
肠癌
肿瘤免疫
信号转导
细胞生物学
发表日期：2021
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Enhancement of target specificity of CRISPR-Cas12a by using a chimeric DNA-RNA guide

利用嵌合 DNA-RNA 向导增强 CRISPR-Cas12a 的靶向特异性

期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gkaa605
Hanseop Kim, Wi-Jae Lee, Yeounsun Oh, Seung-Hun Kang, Junho K Hur, Hyomin Lee, WooJeung Song, Kyung-Seob Lim, Young-Ho Park, Bong-Seok Song, Yeung Bae Jin, Bong-Hyun Jun, Cheulhee Jung, Dong-Seok Lee, Sun-Uk Kim, Seung Hwan Lee
发表日期：2020
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Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment

使用目标特异性 DNA 富集进行基于预测的高灵敏度 CRISPR 脱靶验证

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-020-17418-8
Seung-Hun Kang, Wi-Jae Lee, Ju-Hyun An, Jong-Hee Lee, Young-Hyun Kim, Hanseop Kim, Yeounsun Oh, Young-Ho Park, Yeung Bae Jin, Bong-Hyun Jun, Junho K Hur, Sun-Uk Kim, Seung Hwan Lee
信号转导
发表日期：2020
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Specificity Assessment of CRISPR Genome Editing of Oncogenic EGFR Point Mutation with Single-Base Differences

利用 CRISPR 技术对致癌性 EGFR 点突变（单碱基差异）进行基因组编辑的特异性评估

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules25010052
Bae, Taegeun; Kim, Hanseop; Kim, Jeong Hee; Kim, Yong Jun; Lee, Seung Hwan; Ham, Byung-Joo; Hur, Junho K
EGFR
肿瘤
EGF
肿瘤免疫
发表日期：2019
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