日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The butyrate-producing Gram-positive human gut bacterium, Hoskinsella mucinilytica, selectively targets host mucin N-acetylhexosamines

产生丁酸的革兰氏阳性人类肠道细菌霍氏杆菌(Hoskinsella mucinilytica)选择性地靶向宿主粘蛋白N-乙酰己糖胺。

Pudlo, Nicholas A; Pereira, Gabriel Vasconcelos; Schaus, Sadie R; Yang, Qinnan; Fuentes, Jaime J; Jin, Chunsheng; Hein, Robert; Zhang, Li; Terrapon, Nicolas; Lyssiotis, Costas A; Schmidt, Thomas M; Hansson, Gunnar C; Luis, Ana S; Martens, Eric C

EatA mediated degradation of intestinal mucus is species-specific and driven by MUC2 structural features

EatA介导的肠道黏液降解具有物种特异性,并受MUC2结构特征驱动。

Trillo-Muyo, Sergio; Dolan, Brendan; Svensson, Frida; Vickers, Tim J; Arike, Liisa; García-Bonete, Maria-Jose; Gustafsson, Jenny K; Nielsen, Mathias I; Wandall, Hans H; Fleckenstein, James M; Hansson, Gunnar C; van der Post, Sjoerd

Structure of the MUC5AC VWD3 assembly responsible for the formation of net-like mucin polymers.

负责形成网状粘蛋白聚合物的 MUC5AC VWD3 组装体的结构

Trillo-Muyo Sergio, Ermund Anna, Hansson Gunnar C

The structure of FCGBP is formed as a disulfide-mediated homodimer between its C-terminal domains.

FCGBP 的结构是由其 C 端结构域之间通过二硫键介导的同源二聚体形成的

Ehrencrona Erik, Gallego Pablo, Trillo-Muyo Sergio, Garcia-Bonete Maria-Jose, Recktenwald Christian V, Hansson Gunnar C, Johansson Malin E V

Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron

瘤胃球菌(Ruminococcus torques)是肠道粘蛋白糖蛋白的关键降解菌,可释放寡糖供拟杆菌(Bacteroides thetaiotaomicron)利用。

Schaus, Sadie R; Vasconcelos Pereira, Gabriel; Luis, Ana S; Madlambayan, Emily; Terrapon, Nicolas; Ostrowski, Matthew P; Jin, Chunsheng; Henrissat, Bernard; Hansson, Gunnar C; Martens, Eric C

Intestinal mucus and their glycans: A habitat for thriving microbiota

肠道黏液及其聚糖:微生物群繁衍生息的栖息地

Luis, Ana S; Hansson, Gunnar C

The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins

与血管性血友病因子和其他凝胶形成性粘蛋白相比,肠道MUC2粘蛋白C端通过额外的二硫键而稳定。

Gallego, Pablo; Garcia-Bonete, Maria-Jose; Trillo-Muyo, Sergio; Recktenwald, Christian V; Johansson, Malin E V; Hansson, Gunnar C

A Golgi oxygen sensor controls intestinal mucin glycosylation

高尔基体氧传感器控制肠道粘蛋白糖基化

Hansson, Gunnar C

Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.

空肠粘液层的 Muc2 依赖性微生物定植对饮食敏感,并赋予局部抵抗肠道病原体感染的能力

Birchenough George M H, Schroeder Bjoern O, Sharba Sinan, Arike Liisa, Recktenwald Christian V, Puértolas-Balint Fabiola, Subramani Mahadevan V, Hansson Karl T, Yilmaz Bahtiyar, Lindén Sara K, Bäckhed Fredrik, Hansson Gunnar C

Mucus aberrant properties in CF: Insights from cells and animal models

囊性纤维化患者黏液异常特性:来自细胞和动物模型的启示

Ehre, Camille; Hansson, Gunnar C; Thornton, David J; Ostedgaard, Lynda S