Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination
穿孔素和γ干扰素的表达是CD4+和CD8+ T细胞依赖性保护性免疫所必需的，这种免疫针对的是人类寄生虫克氏锥虫，该免疫由异源质粒DNA启动-重组腺病毒5加强疫苗接种诱导产生。
期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/IAI.01459-08
de Alencar, Bruna C G; Persechini, Pedro M; Haolla, Filipe A; de Oliveira, Gabriel; Silverio, Jaline C; Lannes-Vieira, Joseli; Machado, Alexandre V; Gazzinelli, Ricardo T; Bruna-Romero, Oscar; Rodrigues, Mauricio M
T细胞
CD8
微生物学
T细胞
细胞生物学
CD4
免疫/内分泌
