Haoran Hu相关文献与解析，生知库 | 链接生命科学的每一步

Sujing Yuan # ，Renqiang Sun # ，Hao Shi ，Nicole M Chapman ，Haoran Hu ，Cliff Guy ，Sherri Rankin ，Anil Kc ，Gustavo Palacios ，Xiaoxi Meng ，Xiang Sun ，Peipei Zhou ，Xiaoyang Yang ，Stephen Gottschalk ，Hongbo Chi

肿瘤

Vdac2

炎症

发表日期：2025

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Tumor cells promote immunosuppression in ovarian cancer via a positive feedback loop with MDSCs through the SAA1-IL-1β axis

肿瘤细胞通过SAA1-IL-1β轴与髓源性抑制细胞（MDSC）形成正反馈环路，从而促进卵巢癌中的免疫抑制。

期刊:

影响因子:11.4

doi:PMC12486657

Haoran Hu #，Meiqin Yang #，Baoyou Huang #，Jianyi Ding，Yashi Zhu，Xinxin Xu，Bo Yin，Huijuan Zhou，Tiefeng Huang，Mengjie Li，Yifan Kou，Zilale Rahim，Ang Li，Wei Wang，Lingfei Han

Tumor cells promote immunosuppression in ovarian cancer via a positive feedback loop with MDSCs through the SAA1-IL-1β axis

肿瘤细胞通过SAA1-IL-1β轴与髓源性抑制细胞（MDSC）形成正反馈环路，从而促进卵巢癌中的免疫抑制。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:11.4

doi:10.1186/s13046-025-03536-y

Haoran Hu # ，Meiqin Yang # ，Baoyou Huang # ，Jianyi Ding ，Yashi Zhu ，Xinxin Xu ，Bo Yin ，Huijuan Zhou ，Tiefeng Huang ，Mengjie Li ，Yifan Kou ，Zilale Rahim ，Ang Li ，Wei Wang ，Lingfei Han

Assessing the impact of insulin resistance trajectories on cardiovascular disease risk using longitudinal targeted maximum likelihood estimation

利用纵向目标最大似然估计法评估胰岛素抵抗轨迹对心血管疾病风险的影响

期刊:Cardiovascular Diabetology

影响因子:10.6

doi:10.1186/s12933-025-02651-6

Feng, Yaning; Yin, Liangying; Huang, Haoran; Hu, Yongheng; Lin, Sitong

Inhibiting CMTM4 reverses the immunosuppressive function of myeloid-derived suppressor cells and augments immunotherapy response in cervical cancer

抑制CMTM4可逆转髓源性抑制细胞的免疫抑制功能，并增强宫颈癌的免疫治疗反应。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2025-011776

Jianyi Ding # ，Haoran Hu # ，Yashi Zhu # ，Xinxin Xu ，Bo Yin ，Meiqin Yang ，Huijuan Zhou ，Tiefeng Huang ，Mengjie Li ，Yifan Kou ，Zilale Rahim ，Baoyou Huang ，Ang Li ，Wei Wang ，Lingfei Han

High expression of eIF4A1 promotes angiogenesis through the NF‑κB/VEGFA pathway and predicts poor prognosis in gastric cancer

eIF4A1高表达通过NF-κB/VEGFA通路促进血管生成，并预示胃癌预后不良。

期刊:Oncology Reports

影响因子:3.8

doi:10.3892/or.2025.8951

Xiaoqun Zhu,Lizhou Jia,Xingwang Kuai,Qi Tang,Xinxia Chang,Xiao Zhang,Bing Chen,Hui Zhi,Haoran Hu,Xiaomei Huang,Zhenqing Feng,Wenbin Huang

Pyroptotic-Spatiotemporally Selective Delivery of siRNA against Pyroptosis and Autoimmune Diseases

细胞焦亡-siRNA 的时空选择性递送，对抗细胞焦亡和自身免疫性疾病

期刊:Advanced Materials

影响因子:27.4

doi:10.1002/adma.202407115

Zongyou Pan, Kaiwang Xu, Guanrui Huang, Haoran Hu, Huang Yang, Haotian Shen, Kaijie Qiu, Canlong Wang, Tengjing Xu, Xinning Yu, Jinhua Fang, Jiajie Wang, Yunting Lin, Jiacheng Dai, Yuting Zhong, Hongyun Song, Sunan Zhu, Siheng Wang, Zhuxing Zhou, Chuyue Sun, Zhaopeng Tang, Shiyao Liao, Guang Yang, Z

CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation

CRISPR筛选揭示了影响肠道组织驻留记忆CD8+ T细胞形成的营养依赖性溶酶体和线粒体节点。

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2024.09.013

Jana L Raynor ，Nicholas Collins ，Hao Shi ，Cliff Guy ，Jordy Saravia ，Seon Ah Lim ，Nicole M Chapman ，Peipei Zhou ，Yan Wang ，Yu Sun ，Isabel Risch ，Haoran Hu ，Anil Kc ，Renqiang Sun ，Sharad Shrestha ，Hongling Huang ，Jon P Connelly ，Shondra M Pruett-Miller ，Miguel Reina-Campos ，Ananda W Goldrath ，Yasmine Belkaid ，Hongbo Chi

CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation

CRISPR筛选揭示了影响肠道组织驻留记忆CD8+ T细胞形成的营养依赖性溶酶体和线粒体节点。

期刊:

影响因子:25.5

doi:PMC11590283

Jana L Raynor，Nicholas Collins，Hao Shi，Cliff Guy，Jordy Saravia，Seon Ah Lim，Nicole M Chapman，Peipei Zhou，Yan Wang，Yu Sun，Isabel Risch，Haoran Hu，Anil Kc，Renqiang Sun，Sharad Shrestha，Hongling Huang，Jon P Connelly，Shondra M Pruett-Miller，Miguel Reina-Campos，Ananda W Goldrath，Yasmine Belkaid，Hongbo Chi

A unified model-based framework for doublet or multiplet detection in single-cell multiomics data

基于模型的单细胞多组学数据中双联体或多联体检测的统一框架

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-49448-x

Haoran Hu, Xinjun Wang, Site Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O'Hare, Yanshuo Chen, Molin Yue, Lang Zeng, Ziqi Rong, Tianmeng Chen, Timothy Billiar, Ying Ding, Heng Huang, Richard H Duerr, Wei Chen4

VDAC2 loss elicits tumour destruction and inflammation for cancer therapy

VDAC2缺失可引发肿瘤破坏和炎症，从而促进癌症治疗。

Tumor cells promote immunosuppression in ovarian cancer via a positive feedback loop with MDSCs through the SAA1-IL-1β axis

肿瘤细胞通过SAA1-IL-1β轴与髓源性抑制细胞（MDSC）形成正反馈环路，从而促进卵巢癌中的免疫抑制。

Tumor cells promote immunosuppression in ovarian cancer via a positive feedback loop with MDSCs through the SAA1-IL-1β axis

肿瘤细胞通过SAA1-IL-1β轴与髓源性抑制细胞（MDSC）形成正反馈环路，从而促进卵巢癌中的免疫抑制。

Assessing the impact of insulin resistance trajectories on cardiovascular disease risk using longitudinal targeted maximum likelihood estimation

利用纵向目标最大似然估计法评估胰岛素抵抗轨迹对心血管疾病风险的影响

Inhibiting CMTM4 reverses the immunosuppressive function of myeloid-derived suppressor cells and augments immunotherapy response in cervical cancer

抑制CMTM4可逆转髓源性抑制细胞的免疫抑制功能，并增强宫颈癌的免疫治疗反应。

High expression of eIF4A1 promotes angiogenesis through the NF‑κB/VEGFA pathway and predicts poor prognosis in gastric cancer

eIF4A1高表达通过NF-κB/VEGFA通路促进血管生成，并预示胃癌预后不良。

Pyroptotic-Spatiotemporally Selective Delivery of siRNA against Pyroptosis and Autoimmune Diseases

细胞焦亡-siRNA 的时空选择性递送，对抗细胞焦亡和自身免疫性疾病

CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation

CRISPR筛选揭示了影响肠道组织驻留记忆CD8+ T细胞形成的营养依赖性溶酶体和线粒体节点。

CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation

CRISPR筛选揭示了影响肠道组织驻留记忆CD8+ T细胞形成的营养依赖性溶酶体和线粒体节点。

A unified model-based framework for doublet or multiplet detection in single-cell multiomics data

基于模型的单细胞多组学数据中双联体或多联体检测的统一框架