日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis

结核分枝杆菌中SteAB调控细胞壁水解酶RipA的机制研究

Carloni, Giacomo; Gaday, Quentin; Megrian, Daniela; Petit, Julienne; Martinez, Mariano; Sogues, Adrià; Ben Assaya, Mathilde; Kakonyi, Marcell; Haouz, Ahmed; Alzari, Pedro M; Wehenkel, Anne Marie

The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation.

白血病中发现的 SETD2 L1609P 突变会破坏甲基转移酶活性,降低组蛋白 H3K36 三甲基化。

Michail Christina, Berthelet Jérémy, Mechaly Ariel E, Bui Linh-Chi, Yang Haopeng, Cai Duo, Al Mahi Amira, Xie Aowei, Bisio Valeria, Sirri Valentina, Dupret Jean-Marie, Guidez Fabien, Xu Ximing, Joly Nicolas, Regad Leslie, Viguier Mireille, Deshayes Frédérique, Dulphy Nicolas, Green Michael R, Haouz Ahmed, Rodrigues Lima Fernando

Structural basis of Mycobacterium Fluoroquinolone Resistance Protein D (MfpD), a versatile pathogeny protein from the mfp conservon of Mycobacterium tuberculosis

结核分枝杆菌mfp保守子中的多功能致病蛋白——氟喹诺酮耐药蛋白D (MfpD) 的结构基础

Gedeon, Antoine; Micaletto, Maureen; Megrian, Daniela; Leroy, Elodie Carmen; Barbier, Elorri; Raynal, Bertrand; Haouz, Ahmed; Alzari, Pedro M; Mayer, Claudine; Petrella, Stéphanie

Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement

CREBBP突变淋巴瘤中CD40反应性增强子激活减弱可通过强制CD4 T细胞参与来恢复。

Yang, Haopeng; Zhang, Wenchao; Ravanmehr, Vida; Cui, Guiling; Bowman, Kevin; Chen, Ruidong; Henderson, Jared M; Lockman, Shyanne; Rojas, Estela; Wilson, Ashley; Parsons, Sydney; Mechaly, Ariel; Regad, Leslie; Haouz, Ahmed; Flowers, Christopher R; Neelapu, Sattva; Nastoupil, Loretta; Davis, R Eric; Deng, Qing; Rodrigues-Lima, Fernando; Green, Michael R

Dipeptidase 1 is a functional receptor for a porcine coronavirus

二肽酶1是猪冠状病毒的功能性受体

Dufloo, Jérémy; Fernández, Ignacio; Arbabian, Atousa; Haouz, Ahmed; Temperton, Nigel; Gimenez-Lirola, Luis G; Rey, Félix A; Sanjuán, Rafael

Structural insights into tecovirimat antiviral activity and poxvirus resistance.

特科维瑞马抗病毒活性和痘病毒抗性的结构研究

Vernuccio Riccardo, Martínez León Alejandro, Poojari Chetan S, Buchrieser Julian, Selverian Christopher N, Jaleta Yakin, Meola Annalisa, Guivel-Benhassine Florence, Porrot Françoise, Haouz Ahmed, Chevreuil Maelenn, Raynal Bertrand, Mercer Jason, Simon-Loriere Etienne, Chandran Kartik, Schwartz Olivier, Hub Jochen S, Guardado-Calvo Pablo

Development of a replication-defective mpox virus platform for fundamental and therapeutic research

开发用于基础研究和治疗研究的复制缺陷型痘病毒平台

Chen, Jiannan; Hu, Liyuan; Vernuccio, Riccardo; Shi, Ning; Tian, Jiaxin; Zhang, Yuyi; Tian, Sicheng; Cao, Xinyu; Ha, Zhuo; Lu, Jiahan; Battini, Leandro; Raynal, Bertrand; Haouz, Ahmed; Xue, Jing; Cai, Qiliang; Zhao, Yiqi; Lu, Yongxu; Smith, Geoffrey L; Xie, Youhua; Lu, Huijun; Guardado-Calvo, Pablo; Zhang, Ping; Zhang, Rong

Targeting ACE2 with a camelid antibody inhibits SARS-CoV-2 binding and has protective effects in vivo.

利用骆驼科动物抗体靶向 ACE2 可抑制 SARS-CoV-2 的结合,并在体内发挥保护作用。

Blachier Simon, Vaney Marie-Christine, Conquet Laurine, Staropoli Isabelle, Fernández Ignacio, Giraud Emilie, Arbabian Atousa, Michel Vincent, Szilagyi Fruzsina, Guez Salomé, Boucharlat Alix, Chiaravalli Jeanne, Tran-Rajau Jaouen, Dufour Evelyne, Haouz Ahmed, Petres Stéphane, Planas Delphine, Montagutelli Xavier, Agou Fabrice, Lafaye Pierre, Ayme Gabriel, Schwartz Olivier, Rey Felix A, Enninga Jost, Brelot Anne

Fidelity, specialization, and evolution of Paramecium PolX DNA polymerases involved in programmed double-strand break DNA repair

草履虫PolX DNA聚合酶参与程序性双链断裂DNA修复的保真度、特化和进化

Nourisson, Antonin; Missoury, Sophia; Lucas-Staat, Soizick; Haouz, Ahmed; Delarue, Marc

Ancestral [Fe-S] biogenesis system SMS has a unique mechanism of cluster assembly and sulfur utilization

祖先[Fe-S]生物合成系统SMS具有独特的簇组装和硫利用机制

Dussouchaud, Macha; Martinez-Carranza, Markel; Garcia, Pierre-Simon; Clémancey, Martin; Blondin, Geneviève; Betton, Jean Michel; Haouz, Ahmed; Gribaldo, Simonetta; Ollagnier de Choudens, Sandrine; Sauguet, Ludovic; Mechaly, Ariel; Barras, Frédéric