N-glycan-modified α-L-iduronidase produced by transgenic silkworms ameliorates clinical signs in a Japanese macaque with mucopolysaccharidosis I.
转基因蚕产生的N-糖基化修饰的α-L-艾杜糖醛酸酶可改善患有粘多糖贮积症I型的日本猕猴的临床症状
期刊:Commun Med (Lond)
影响因子:
doi:10.1038/s43856-025-00841-7
Shinoda Chika, Kitakaze Keisuke, Sasai Yuya, Nishioka So-Ichiro, Kobayashi Isao, Sumitani Megumi, Tatematsu Ken-Ichiro, Iizuka Tetsuya, Harazono Akira, Mitani Ai, Kaneko Akihisa, Imamura Masanori, Miyabe-Nishiwaki Takako, Go Yasuhiro, Hirata Akihiro, Takeuchi Yoshie, Mizuno Teru, Kiriyama Kei, Tsukimoto Jun, Nadanaka Satomi, Ishii-Watabe Akiko, Kinoshita Takashi, Kitagawa Hiroshi, Suzuki Yasuyuki, Oishi Takao, Sezutsu Hideki, Itoh Kohji
