日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolite import by SLC33A1 is required for ATF6 activation during endoplasmic reticulum stress

内质网应激期间,SLC33A1介导的代谢物输入是ATF6激活所必需的。

George, Ginto; Harding, Heather P; Kay, Richard; Ron, David; Ordoñez, Adriana

Higher-order phosphatase-substrate contacts terminate the integrated stress response

高级磷酸酶-底物接触终止整合应激反应

Yan, Yahui; Harding, Heather P; Ron, David

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B

ISRIB的结合揭示了核苷酸交换因子eIF2B中的一个调控位点。

Zyryanova, Alisa F; Weis, Félix; Faille, Alexandre; Alard, Akeel Abo; Crespillo-Casado, Ana; Sekine, Yusuke; Harding, Heather P; Allen, Felicity; Parts, Leopold; Fromont, Christophe; Fischer, Peter M; Warren, Alan J; Ron, David

Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling

撤稿声明:未折叠蛋白反应元件IRE1α感知入侵内质网的细菌蛋白以激活RIG-I和先天免疫信号传导

Cho, Jin A; Lee, Ann-Hwee; Platzer, Barbara; Cross, Benedict C S; Gardner, Brooke M; De Luca, Heidi; Luong, Phi; Harding, Heather P; Glimcher, Laurie H; Walter, Peter; Fiebiger, Edda; Ron, David; Kagan, Jonathan C; Lencer, Wayne I

Skeletal muscle-specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21-mediated non-cell-autonomous energy metabolism

骨骼肌特异性真核翻译起始因子2α磷酸化调控氨基酸代谢和成纤维细胞生长因子21介导的非细胞自主能量代谢

Miyake, Masato; Nomura, Akitoshi; Ogura, Atsushi; Takehana, Kenji; Kitahara, Yoshihiro; Takahara, Kazuna; Tsugawa, Kazue; Miyamoto, Chinobu; Miura, Naoko; Sato, Ryosuke; Kurahashi, Kiyoe; Harding, Heather P; Oyadomari, Miho; Ron, David; Oyadomari, Seiichi

PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis

PERK激活通过减弱癌前颗粒细胞前体细胞凋亡促进髓母细胞瘤的肿瘤发生

Ho, Yeung; Li, Xiting; Jamison, Stephanie; Harding, Heather P; McKinnon, Peter J; Ron, David; Lin, Wensheng

Dual role of the integrated stress response in medulloblastoma tumorigenesis

整合应激反应在髓母细胞瘤发生中的双重作用

Stone, Sarrabeth; Ho, Yeung; Li, Xiting; Jamison, Stephanie; Harding, Heather P; Ron, David; Lin, Wensheng

Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker.

通过跨结构域连接子的反式原聚体结合对 BiP 活性进行生理调节

Preissler Steffen, Chambers Joseph E, Crespillo-Casado Ana, Avezov Edward, Miranda Elena, Perez Juan, Hendershot Linda M, Harding Heather P, Ron David

Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

PDI扩散受阻和钙耗竭内质网平衡的还原性转变

Avezov, Edward; Konno, Tasuku; Zyryanova, Alisa; Chen, Weiyue; Laine, Romain; Crespillo-Casado, Ana; Melo, Eduardo Pinho; Ushioda, Ryo; Nagata, Kazuhiro; Kaminski, Clemens F; Harding, Heather P; Ron, David

A method to quantify FRET stoichiometry with phasor plot analysis and acceptor lifetime ingrowth

一种利用相量图分析和受体寿命增长来量化FRET化学计量的方法

Chen, WeiYue; Avezov, Edward; Schlachter, Simon C; Gielen, Fabrice; Laine, Romain F; Harding, Heather P; Hollfelder, Florian; Ron, David; Kaminski, Clemens F