An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides
LNA-酰胺修饰可增强硫代磷酸酯外显子跳跃寡核苷酸的细胞摄取和活性
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-31636-2
Baker, Ysobel R; Thorpe, Cameron; Chen, Jinfeng; Poller, Laura M; Cox, Lina; Kumar, Pawan; Lim, Wooi F; Lie, Lillian; McClorey, Graham; Epple, Sven; Singleton, Daniel; McDonough, Michael A; Hardwick, Jack S; Christensen, Kirsten E; Wood, Matthew J A; Hall, James P; El-Sagheer, Afaf H; Brown, Tom