Hardy P Brian相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl-lysine reader protein MPP8

应用MALDI质谱分析法鉴定靶向甲基赖氨酸识别蛋白MPP8的共价片段

期刊:SLAS Discovery

影响因子:2.7

doi:10.1016/j.slasd.2026.100296

Rubiano, Juanita L Sanchez; Buttery, Peter H; Gurard-Levin, Zachary A; Norris-Drouin, Jacqueline L; Mather, Lilyan M; Hardy, P Brian; Frye, Stephen V; James, Lindsey I

发表日期：2026

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A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-Î³2 to treat Alzheimer's disease.

用于发现磷脂酶 PLC-γ2 小分子激活剂以治疗阿尔茨海默病的高通量检测平台

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.108356

Carr Adam J, Hajicek Nicole, Tsai Andy P, Acharya Padam P, Hardy P Brian, Meyer Emma, Wyss-Coray Tony, Pearce Kenneth H, Sondek John, Zhang Qisheng

发表日期：2025

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Expansion of DNA-Encoded Library Hits Using Generative Chemistry and Ultra-Large Compound Catalogs

利用生成化学和超大型化合物目录扩展DNA编码化合物库

doi:10.1101/2025.09.30.679600

Novy, Brandon; Lin, Shu-Hang; Shell, Devan J; Maxfield, Travis; Merten, Eric M; Wellnitz, James; Guduru, Shiva K R; Hardy, P Brian; Pearce, Kenneth H; Popov, Konstantin I

发表日期：2025

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A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader Proteins

用于高通量筛选和表征甲基赖氨酸读取蛋白抑制剂的通用TR-FRET检测平台

期刊:SLAS Discovery

影响因子:2.7

doi:10.1177/2472555219844569

Rectenwald, Justin M; Hardy, P Brian; Norris-Drouin, Jacqueline L; Cholensky, Stephanie H; James, Lindsey I; Frye, Stephen V; Pearce, Kenneth H

发表日期：2019

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Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors

利用蛋白激酶靶向化合物库发现新型肌醇磷酸激酶抑制剂

期刊:SLAS Discovery

影响因子:2.7

doi:10.1177/2472555218775323

Puhl-Rubio, Ana C; Stashko, Michael A; Wang, Huanchen; Hardy, P Brian; Tyagi, Vikas; Li, Bing; Wang, Xiaodong; Kireev, Dmitri; Jessen, Henning J; Frye, Stephen V; Shears, Stephen B; Pearce, Kenneth H

发表日期：2018

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