日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural analysis of the lncRNA SChLAP1 reveals protein binding interfaces and a conformationally heterogenous retroviral insertion.

lncRNA SChLAP1 的结构分析揭示了蛋白质结合界面和构象异质性逆转录病毒插入

Falese James P, McFadden Emily J, D'Inzeo Christopher A, Hargrove Amanda E

Stability-Based Proteomics for Investigation of Structured RNA-Protein Interactions

基于稳定性的蛋白质组学在结构化RNA-蛋白质相互作用研究中的应用

Bailey, Morgan A; Martyr, Justin G; Hargrove, Amanda E; Fitzgerald, Michael C

High-resolution structure of stem-loop 4 from the 5'-UTR of SARS-CoV-2 solved by solution state NMR

利用溶液核磁共振技术解析了SARS-CoV-2 5'-UTR茎环4的高分辨率结构

Vögele, Jennifer; Hymon, Daniel; Martins, Jason; Ferner, Jan; Jonker, Hendrik R A; Hargrove, Amanda E; Weigand, Julia E; Wacker, Anna; Schwalbe, Harald; Wöhnert, Jens; Duchardt-Ferner, Elke

Recognizing the power of machine learning and other computational methods to accelerate progress in small molecule targeting of RNA

认识到机器学习和其他计算方法在加速小分子靶向RNA研究进展方面的强大作用

Bagnolini, Greta; Luu, TinTin B; Hargrove, Amanda E

Probing Bioactive Chemical Space to Discover RNA-Targeted Small Molecules

探索生物活性化学空间以发现靶向RNA的小分子

Wicks, Sarah L; Morgan, Brittany S; Wilson, Alexander W; Hargrove, Amanda E

Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability In Vitro

多重检测分析聚焦小分子库揭示了lncRNA MALAT1三链体稳定性在体外的预测性双向调控

Zafferani, Martina; Martyr, Justin G; Muralidharan, Dhanasheel; Montalvan, Nadeska I; Cai, Zhengguo; Hargrove, Amanda E

R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures

R-BIND 2.0:生物活性RNA靶向小分子及其相关RNA二级结构的最新数据库

Donlic, Anita; Swanson, Emily G; Chiu, Liang-Yuan; Wicks, Sarah L; Juru, Aline Umuhire; Cai, Zhengguo; Kassam, Kamillah; Laudeman, Chris; Sanaba, Bilva G; Sugarman, Andrew; Han, Eunseong; Tolbert, Blanton S; Hargrove, Amanda E

RT-qPCR as a screening platform for mutational and small molecule impacts on structural stability of RNA tertiary structures

RT-qPCR作为筛选平台,用于研究突变和小分子对RNA三级结构稳定性的影响

Zafferani, Martina; Muralidharan, Dhanasheel; Montalvan, Nadeska I; Hargrove, Amanda E

Targeting RNA with small molecules: from fundamental principles towards the clinic

利用小分子靶向RNA:从基本原理到临床应用

Falese, James P; Donlic, Anita; Hargrove, Amanda E

Small molecule targeting of biologically relevant RNA tertiary and quaternary structures

靶向生物学相关RNA三级和四级结构的小分子

Zafferani, Martina; Hargrove, Amanda E