Harikanth相关文献与解析，生知库 | 链接生命科学的每一步

Jia, Xudong; Gao, Yuanzhu; Huang, Yuxuan; Sun, Linjun; Li, Siduo; Li, Hongmei; Zhang, Xueqing; Li, Yinyin; He, Jian; Wu, Wenbi; Venkannagari, Harikanth; Yang, Kai; Baker, Matthew L; Zhang, Qinfen

微生物学

发表日期：2023

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[1,2,4]Triazolo[3,4- b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes

[1,2,4]三唑并[3,4-b]苯并噻唑支架作为多功能烟酰胺模拟物，可对不同的 PARP 酶进行纳摩尔级抑制

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.2c01460

Sudarshan Murthy, Maria Giulia Nizi, Mirko M Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E Lippok, Chiara Vagaggini, Sven T Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, L

PARP

发表日期：2023

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Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes

IgLON 中高度保守的分子特征与其独特的结构和生物学结果形成对比

期刊:Journal of Molecular Biology

影响因子:4.7

doi:10.1016/j.jmb.2020.07.014

Harikanth Venkannagari, James M Kasper, Anurag Misra, Scott A Rush, Shanghua Fan, Hubert Lee, Hong Sun, Suchithra Seshadrinathan, Mischa Machius, Jonathan D Hommel, Gabby Rudenko

发表日期：2020

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Self-assembly of the bZIP transcription factor ΔFosB

bZIP 转录因子 ΔFosB 的自组装

期刊:Current Research in Structural Biology

影响因子:2.7

doi:10.1016/j.crstbi.2019.12.001

Zhou Yin, Harikanth Venkannagari, Haley Lynch, Galina Aglyamova, Mukund Bhandari, Mischa Machius, Eric J Nestler, Alfred J Robison, Gabby Rudenko

信号转导

发表日期：2020

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Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage

小分子化学探针拯救细胞免于单 ADP 核糖基转移酶 ARTD10/PARP10 诱导的细胞凋亡，并使癌细胞对 DNA 损伤敏感

期刊:Cell Chemical Biology

影响因子:6.6

doi:10.1016/j.chembiol.2016.08.012

Harikanth Venkannagari, Patricia Verheugd, Jarkko Koivunen, Teemu Haikarainen, Ezeogo Obaji, Yashwanth Ashok, Mohit Narwal, Taina Pihlajaniemi, Bernhard Lüscher, Lari Lehtiö

Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei

在前周期性布氏锥虫中，ADP-核糖代谢紊乱，核聚（ADP-核糖）积累，在过氧化氢存在下导致不同的细胞死亡途径

期刊:Parasites & Vectors

影响因子:3

doi:10.1186/s13071-016-1461-1

Mariana Schlesinger, Salomé C Vilchez Larrea, Teemu Haikarainen, Mohit Narwal, Harikanth Venkannagari, Mirtha M Flawiá, Lari Lehtiö, Silvia H Fernández Villamil

Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors

基于活性的人类单 ADP 核糖基转移酶 ARTD7/PARP15 和 ARTD10/PARP10 检测旨在筛选和分析抑制剂

期刊:European Journal of Pharmaceutical Sciences

影响因子:4.3

doi:10.1016/j.ejps.2013.02.012

Harikanth Venkannagari, Adyary Fallarero, Karla L H Feijs, Bernhard Lüscher, Lari Lehtiö

Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4

Wnt 信号抑制剂 WIKI4 抑制端锚聚合酶的结构基础和选择性

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0065404

Teemu Haikarainen, Harikanth Venkannagari, Mohit Narwal, Ezeogo Obaji, Hao-Wei Lee, Yves Nkizinkiko, Lari Lehtiö

Predictive modeling and cryo-EM: A synergistic approach to modeling macromolecular structure

预测建模与冷冻电镜：一种用于模拟大分子结构的协同方法

Architecture of the baculovirus nucleocapsid revealed by cryo-EM

冷冻电镜揭示杆状病毒核衣壳的结构

[1,2,4]Triazolo[3,4- b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes

[1,2,4]三唑并[3,4-b]苯并噻唑支架作为多功能烟酰胺模拟物，可对不同的 PARP 酶进行纳摩尔级抑制

Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes

IgLON 中高度保守的分子特征与其独特的结构和生物学结果形成对比

Self-assembly of the bZIP transcription factor ΔFosB

bZIP 转录因子 ΔFosB 的自组装

Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage

小分子化学探针拯救细胞免于单 ADP 核糖基转移酶 ARTD10/PARP10 诱导的细胞凋亡，并使癌细胞对 DNA 损伤敏感

Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei

在前周期性布氏锥虫中，ADP-核糖代谢紊乱，核聚（ADP-核糖）积累，在过氧化氢存在下导致不同的细胞死亡途径

Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors

基于活性的人类单 ADP 核糖基转移酶 ARTD7/PARP15 和 ARTD10/PARP10 检测旨在筛选和分析抑制剂

Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4

Wnt 信号抑制剂 WIKI4 抑制端锚聚合酶的结构基础和选择性