日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders.

利用选择性 Aurora 激酶 A 降解剂靶向神经母细胞瘤中的 N-Myc

Tang Jian, Moorthy Ramkumar, Hirsch Laura E, Demir Özlem, Baker Zachary D, Naumann Jordan A, Jones Katherine F M, Grillo Michael J, Haefner Ella S, Shi Ke, Levy Michaella J, Gupta Harshita B, Aihara Hideki, Harris Reuben S, Amaro Rommie E, Levinson Nicholas M, Harki Daniel A

A Novel Fluorescence Polarization Binding Assay for the Main Protease (M(pro)) of SARS-CoV‑2

一种用于检测SARS-CoV-2主蛋白酶(M(pro))的新型荧光偏振结合分析方法

Wyllie, Mackenzie K; Biswas, Rayhan G; Vishwakarma, Jyoti; Esler, Morgan A; Rollie, Joseph A; Aihara, Hideki; Harris, Reuben S; Harki, Daniel A

Identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)

NF-κB诱导激酶(NIK)催化结构域上新型变构结合位点的鉴定

Anderson, Jared J; Harki, Daniel A

A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid RNA-binding domain

一种紧凑的茎环DNA适体靶向SARS-CoV-2核衣壳RNA结合域中的尿嘧啶结合口袋

Esler, Morgan A; Belica, Christopher A; Rollie, Joseph A; Brown, William L; Moghadasi, Seyed Arad; Shi, Ke; Harki, Daniel A; Harris, Reuben S; Aihara, Hideki

Development of 3'-Deoxy-3',4'-didehydro-nucleoside Prodrug Inhibitors of West Nile and Zika Viruses

西尼罗河病毒和寨卡病毒的3'-脱氧-3',4'-二脱氢核苷前药抑制剂的开发

Kennelly, Samantha A; Sawyer, Jacob M; Payne, Anne F; Ciota, Alexander T; Harki, Daniel A

Development of Allosteric Small Molecule APOBEC3B Inhibitors from In Silico Screening

基于计算机筛选的变构小分子APOBEC3B抑制剂的开发

Jones, Katherine F M; Demir, Özlem; Wyllie, Mackenzie K; Grillo, Michael J; Morris, Clare; Hirakis, Sophia P; Kardile, Rahul Dadabhau; Walters, Michael A; Harris, Reuben S; Amaro, Rommie E; Harki, Daniel A

Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease

干扰冠状病毒 3' 至 5' 外切核糖核酸酶的核苷酸切除

Chinthapatla, Rukesh; Sotoudegan, Mohamad; Srivastava, Pankaj; Anderson, Thomas K; Moustafa, Ibrahim M; Passow, Kellan T; Kennelly, Samantha A; Moorthy, Ramkumar; Dulin, David; Feng, Joy Y; Harki, Daniel A; Kirchdoerfer, Robert N; Cameron, Craig E; Arnold, Jamie J

Recent progress and structural analyses of domain-selective BET inhibitors

结构域选择性BET抑制剂的最新进展和结构分析

Divakaran, Anand; Harki, Daniel A; Pomerantz, William C K

Synthesis and photophysical characterization of fluorescent indole nucleoside analogues

荧光吲哚核苷类似物的合成及光物理表征

Sawyer, Jacob M; Passow, Kellan T; Harki, Daniel A

APOBEC3A Catalytic Inactivity Mutation Induces Tertiary Structure Destabilization

APOBEC3A催化失活突变导致三级结构不稳定

Jones, Katherine F M; Shehata, Mohamed; Carpenter, Michael A; Amaro, Rommie E; Harki, Daniel A