日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

通过一系列ATP类似物靶向脯氨酰tRNA合成酶,加速弓形虫病药物的发现

Yogavel, Manickam; Bougdour, Alexandre; Mishra, Siddhartha; Malhotra, Nipun; Chhibber-Goel, Jyoti; Bellini, Valeria; Harlos, Karl; Laleu, Benoît; Hakimi, Mohamed-Ali; Sharma, Amit

Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein

纳尔莫病毒受体结合蛋白C端头部区域的晶体结构和溶液状态

Stelfox, Alice J; Oguntuyo, Kasopefoluwa Y; Rissanen, Ilona; Harlos, Karl; Rambo, Robert; Lee, Benhur; Bowden, Thomas A

Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies

免疫诱导的单克隆抗体对新世界沙粒病毒的中和作用的对比模式

Ng, Weng M; Sahin, Mehmet; Krumm, Stefanie A; Seow, Jeffrey; Zeltina, Antra; Harlos, Karl; Paesen, Guido C; Pinschewer, Daniel D; Doores, Katie J; Bowden, Thomas A

Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1)

分泌型卷曲相关蛋白 Sizzled 的动态变化及其与骨形态发生蛋白-1 (BMP-1) 结合的潜在意义

Sharma, Urvashi; Vadon-Le Goff, Sandrine; Harlos, Karl; Zhao, Yuguang; Mariano, Natacha; Bijakowski, Cecile; Bourhis, Jean-Marie; Moali, Catherine; Hulmes, David J S; Aghajari, Nushin

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.

原核病毒包膜蛋白的结构拓展了膜融合蛋白的研究领域

El Omari Kamel, Li Sai, Kotecha Abhay, Walter Thomas S, Bignon Eduardo A, Harlos Karl, Somerharju Pentti, De Haas Felix, Clare Daniel K, Molin Mika, Hurtado Felipe, Li Mengqiu, Grimes Jonathan M, Bamford Dennis H, Tischler Nicole D, Huiskonen Juha T, Stuart David I, Roine Elina

Insights from the crystal structure of the chicken CREB3 bZIP suggest that members of the CREB3 subfamily transcription factors may be activated in response to oxidative stress

鸡 CREB3 bZIP 晶体结构的解析表明,CREB3 亚家族转录因子成员可能在氧化应激反应中被激活。

Sabaratnam, Keshalini; Renner, Max; Paesen, Guido; Harlos, Karl; Nair, Venugopal; Owens, Raymond J; Grimes, Jonathan M

Shielding and activation of a viral membrane fusion protein

病毒膜融合蛋白的屏蔽和激活

Halldorsson, Steinar; Li, Sai; Li, Mengqiu; Harlos, Karl; Bowden, Thomas A; Huiskonen, Juha T

Structures of monomeric and oligomeric forms of the Toxoplasma gondii perforin-like protein 1

弓形虫穿孔素样蛋白1的单体和寡聚体形式的结构

Ni, Tao; Williams, Sophie I; Rezelj, Saša; Anderluh, Gregor; Harlos, Karl; Stansfeld, Phillip J; Gilbert, Robert J C

High-speed fixed-target serial virus crystallography

高速固定靶串行病毒晶体学

Roedig, Philip; Ginn, Helen M; Pakendorf, Tim; Sutton, Geoff; Harlos, Karl; Walter, Thomas S; Meyer, Jan; Fischer, Pontus; Duman, Ramona; Vartiainen, Ismo; Reime, Bernd; Warmer, Martin; Brewster, Aaron S; Young, Iris D; Michels-Clark, Tara; Sauter, Nicholas K; Kotecha, Abhay; Kelly, James; Rowlands, David J; Sikorsky, Marcin; Nelson, Silke; Damiani, Daniel S; Alonso-Mori, Roberto; Ren, Jingshan; Fry, Elizabeth E; David, Christian; Stuart, David I; Wagner, Armin; Meents, Alke

A Two-Tailed Phosphopeptide Crystallizes to Form a Lamellar Structure

双尾磷酸肽结晶形成层状结构

Pellach, Michal; Mondal, Sudipta; Harlos, Karl; Mance, Deni; Baldus, Marc; Gazit, Ehud; Shimon, Linda J W