日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING

发现 STING 无活性形式的新型 cGAMP 竞争性配体

Tony Siu, Michael D Altman, Gretchen A Baltus, Matthew Childers, J Michael Ellis, Hakan Gunaydin, Harold Hatch, Thu Ho, James Jewell, Brian M Lacey, Charles A Lesburg, Bo-Sheng Pan, Berengere Sauvagnat, Gottfried K Schroeder, Serena Xu

MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis

实体肿瘤中的 MCL1 和 BCL-xL 水平可预测 dinaciclib 诱导的细胞凋亡

Robert N Booher, Harold Hatch, Brian M Dolinski, Thi Nguyen, Lauren Harmonay, Ali-Samer Al-Assaad, Mark Ayers, Michael Nebozhyn, Andrey Loboda, Heather A Hirsch, Theresa Zhang, Bin Shi, Carrie E Merkel, Minilik H Angagaw, Yaolin Wang, Brian J Long, Xianlu Q Lennon, Nathan Miselis, Vincenzo Pucci, Ja

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo

MK-2206 是一种变构 Akt 抑制剂,可在体内外通过标准化疗药物或分子靶向药物增强抗肿瘤功效

Hiroshi Hirai, Hiroshi Sootome, Yoko Nakatsuru, Katsuyoshi Miyama, Shunsuke Taguchi, Kyoko Tsujioka, Yoko Ueno, Harold Hatch, Pradip K Majumder, Bo-Sheng Pan, Hidehito Kotani

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

FGFR2 扩增的胃癌细胞系需要 FGFR2 和 Erbb3 信号传导才能生长和存活

Kaiko Kunii, Lenora Davis, Julie Gorenstein, Harold Hatch, Masakazu Yashiro, Alessandra Di Bacco, Cem Elbi, Bart Lutterbach