日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability

将 H4K20me3 映射到衰老细胞的染色质景观上,表明其通过保持遗传和表观遗传稳定性来控制细胞衰老和肿瘤抑制

David M Nelson, Farah Jaber-Hijazi, John J Cole, Neil A Robertson, Jeffrey S Pawlikowski, Kevin T Norris, Steven W Criscione, Nikolay A Pchelintsev, Desiree Piscitello, Nicholas Stong, Taranjit Singh Rai, Tony McBryan, Gabriel L Otte, Colin Nixon, William Clark, Harold Riethman, Hong Wu, Gunnar Scho

Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres

亚端粒 p53 结合可防止人类端粒处 DNA 损伤的积累

Stephen Tutton, Greggory A Azzam, Nicholas Stong, Olga Vladimirova, Andreas Wiedmer, Jessica A Monteith, Kate Beishline, Zhuo Wang, Zhong Deng, Harold Riethman, Steven B McMahon, Maureen Murphy, Paul M Lieberman

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence

BRCA1 单倍体不足导致细胞类型特异性基因组不稳定和过早衰老

Maja Sedic, Adam Skibinski, Nelson Brown, Mercedes Gallardo, Peter Mulligan, Paula Martinez, Patricia J Keller, Eugene Glover, Andrea L Richardson, Janet Cowan, Amanda E Toland, Krithika Ravichandran, Harold Riethman, Stephen P Naber, Anders M Näär, Maria A Blasco, Philip W Hinds, Charlotte Kuperwas

Functional characterization of the TERRA transcriptome at damaged telomeres

端粒受损时 TERRA 转录组的功能表征

Antonio Porro, Sascha Feuerhahn, Julien Delafontaine, Harold Riethman, Jacques Rougemont, Joachim Lingner

Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline

使用改进的亚端粒组装和新型注释流程组织亚端粒 CTCF 和黏连蛋白结合位点

Nicholas Stong, Zhong Deng, Ravi Gupta, Sufen Hu, Shiela Paul, Amber K Weiner, Evan E Eichler, Tina Graves, Catrina C Fronick, Laura Courtney, Richard K Wilson, Paul M Lieberman, Ramana V Davuluri, Harold Riethman

TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres

TERRA RNA 与 TRF2 结合促进异染色质的形成和端粒处的 ORC 募集

Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman