日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bridging Heterocycle-Mediated Hydrogen Bonding Facilitates Permeability of Polar Macrobicycles

桥联杂环介导的氢键促进极性大环化合物的渗透性

Cooper, Gabriella I D; Dai, Botao; Durham, Noah; Walker, Gilbert L; Yu, Hongyi; Mendoza, Angel; Bernardino, Salvador J; Wu, Yun-Dong; Harran, Patrick G

Computational generation of an annotated gigalibrary of synthesizable, composite peptidic macrocycles

利用计算方法生成可合成的复合肽大环化合物的带注释的巨型化合物库

Saha, Ishika; Dang, Eric K; Svatunek, Dennis; Houk, Kendall N; Harran, Patrick G

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity

合成的重氮酰胺DZ-2384对微管曲率和动力学有显著影响,且无神经毒性。

Wieczorek, Michal; Tcherkezian, Joseph; Bernier, Cynthia; Prota, Andrea E; Chaaban, Sami; Rolland, Yannève; Godbout, Claude; Hancock, Mark A; Arezzo, Joseph C; Ocal, Ozhan; Rocha, Cecilia; Olieric, Natacha; Hall, Anita; Ding, Hui; Bramoullé, Alexandre; Annis, Matthew G; Zogopoulos, George; Harran, Patrick G; Wilkie, Thomas M; Brekken, Rolf A; Siegel, Peter M; Steinmetz, Michel O; Shore, Gordon C; Brouhard, Gary J; Roulston, Anne

On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan

色氨酸区域发散烷基化反应中桥环大环吡咯并吲哚啉的普遍性

Rose, Tristin E; Curtin, Brice H; Lawson, Kenneth V; Simon, Adam; Houk, K N; Harran, Patrick G

Tailored fragments of roseophilin selectively antagonize Mcl-1 in vitro

玫瑰蛋白的定制片段在体外选择性地拮抗 Mcl-1

Bracken, Jack D; Carlson, Andrew D; Frederich, James H; Nguyen, Mai; Shore, Gordon C; Harran, Patrick G

Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan

通过色氨酸的大环形成烷基化反应,模板诱导大环多样性

Lawson, Kenneth V; Rose, Tristan E; Harran, Patrick G

Substituted 2,2'-bipyrroles and pyrrolylfurans via intermediate isoxazolylpyrroles

通过中间体异噁唑基吡咯合成取代的2,2'-联吡咯和吡咯基呋喃

Frederich, James H; Matsui, Jennifer K; Chang, Randy O; Harran, Patrick G

Synthetic (±)-axinellamines deficient in halogen

合成的(±)-axinellamines缺乏卤素

Ding, Hui; Roberts, Andrew G; Harran, Patrick G

Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity.

合成重氮酰胺类似物在无明显毒性的情况下具有治疗抗癌功效

Williams Noelle S, Burgett Anthony W G, Atkins Ashley S, Wang Xiaodong, Harran Patrick G, McKnight Steven L