An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity
一种金刚烷基取代的类视黄醇衍生物，可通过诱导细胞凋亡抑制癌细胞生长和血管生成，并与小型异二聚体伴侣核受体结合：修饰其羧基对细胞凋亡、增殖和蛋白酪氨酸磷酸酶活性的影响
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm0613323
Dawson, Marcia I; Xia, Zebin; Liu, Gang; Ye, Mao; Fontana, Joseph A; Farhana, Lulu; Patel, Bhamik B; Arumugarajah, Sankari; Bhuiyan, Mohammad; Zhang, Xiao-Kun; Han, Young-Hoon; Stallcup, William B; Fukushi, Jun-ichi; Mustelin, Tomas; Tautz, Lutz; Su, Ying; Harris, Danni L; Waleh, Nahid; Hobbs, Peter D; Jong, Ling; Chao, Wan-Ru; Schiff, Leonard J; Sani, Brahma P
肿瘤
凋亡
表观遗传
肿瘤免疫
信号转导
细胞生物学
血管生成
