日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Cyclic-di-AMP Adjuvanted CPAF Protein Vaccine Is Immunogenic in Swine, but It Fails to Reduce Genital Chlamydia trachomatis Burden.

环二腺苷酸佐剂CPAF蛋白疫苗在猪体内具有免疫原性,但未能降低生殖器沙眼衣原体感染负担

Bettin Leonie, Stadler Maria, Unterweger Christine, Dippel Maximiliane, Harris Jonathan M, Buzanich-Ladinig Andrea, Poston Taylor B, Darville Toni, Käser Tobias

Viral-vectored boosting of OmcB- or CPAF-specific T-cell responses fail to enhance protection from Chlamydia muridarum in infection-immune mice and elicits a non-protective CD8-dominant response in naïve mice

病毒载体增强 OmcB 或 CPAF 特异性 T 细胞反应未能提高感染免疫小鼠对鼠衣原体的保护力,反而会在未感染小鼠中诱导出无保护作用的 CD8 优势反应。

Poston, Taylor B; Girardi, Jenna; Polson, A Grace; Bhardwaj, Aakash; Yount, Kacy S; Jaras Salas, Ian; Trim, Logan K; Li, Yanli; O'Connell, Catherine M; Leahy, Darren; Harris, Jonathan M; Beagley, Kenneth W; Goonetilleke, Nilu; Darville, Toni

Correlation of Experimental and Calculated Inhibition Constants of Protease Inhibitor Complexes

蛋白酶抑制剂复合物的实验抑制常数与计算抑制常数的相关性

Goettig, Peter; Chen, Xingchen; Harris, Jonathan M

Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase

人中性粒细胞弹性蛋白酶对蛋氨酸亚砜和砜的鉴别

Leahy, Darren; Grant, Cameron; Jackson, Alex; Duff, Alex; Tardiota, Nicholas; Van Haeften, Jessica; Chen, Xingchen; Peake, Jonathan M; Kruppa, Michael D; Smith, Eliot T; Johnson, David A; Lott, William B; Harris, Jonathan M

A Versatile and Robust Serine Protease Inhibitor Scaffold from Actinia tenebrosa.

来自暗色海葵的多功能且稳健的丝氨酸蛋白酶抑制剂骨架

Chen Xingchen, Leahy Darren, Van Haeften Jessica, Hartfield Perry, Prentis Peter J, van der Burg Chloé A, Surm Joachim M, Pavasovic Ana, Madio Bruno, Hamilton Brett R, King Glenn F, Undheim Eivind A B, Brattsand Maria, Harris Jonathan M

Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II

基于环肽MCoTI-II的强效、选择性和细胞穿透性激肽释放酶相关肽酶4抑制剂

Swedberg, Joakim E; Ghani, Hafiza Abdul; Harris, Jonathan M; de Veer, Simon J; Craik, David J

Mutation of the androgen receptor causes oncogenic transformation of the prostate

雄激素受体突变会导致前列腺癌变

Han, Guangzhou; Buchanan, Grant; Ittmann, Michael; Harris, Jonathan M; Yu, Xiaoqing; Demayo, Francesco J; Tilley, Wayne; Greenberg, Norman M

Interaction of the endothelial nitric oxide synthase with the CAT-1 arginine transporter enhances NO release by a mechanism not involving arginine transport

内皮细胞一氧化氮合酶与 CAT-1 精氨酸转运蛋白的相互作用通过不涉及精氨酸转运的机制增强 NO 释放

Chunying Li, Wei Huang, M Brennan Harris, Jonathan M Goolsby, Richard C Venema

Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbria-mediated twitching motility

铜绿假单胞菌反应调节蛋白AlgR的磷酸化对于IV型菌毛介导的颤搐运动至关重要

Whitchurch, Cynthia B; Erova, Tatiana E; Emery, Jacqui A; Sargent, Jennifer L; Harris, Jonathan M; Semmler, Annalese B T; Young, Michael D; Mattick, John S; Wozniak, Daniel J