日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter

一项采用留置脑脊液导管测量阿尔茨海默病中Aβ寡聚体置换情况的CT1812 1b期随机临床试验

LaBarbera, Kelsie M; Sheline, Yvette I; Izzo, Nicholas J; Yuede, Carla M; Waybright, Lora; Yurko, Raymond; Edwards, Hannah M; Gardiner, Woodrow D; Blennow, Kaj; Zetterberg, Henrik; Börjesson-Hanson, Anne; Morgan, Roger; Davis, Charles S; Guttendorf, Robert J; Schneider, Lon S; DeKosky, Steven; LeVine, Harry 3rd; Grundman, Michael; Caggiano, Anthony O; Cirrito, John R; Catalano, Susan M; Hamby, Mary E

A case of paraproteinemia-associated scleredema successfully treated with thalidomide

一例副蛋白血症相关性硬皮病患者经沙利度胺成功治疗。

Barnes, Martin; Kumar, Vikas; Le, Thuy-Hong; Nabeel, Shaha; Singh, Jameel; Rana, Vishal; Kaell, Alan; Barnes, Harry 3rd

Down syndrome: age-dependence of PiB binding in postmortem frontal cortex across the lifespan

唐氏综合征:死后额叶皮层中PiB结合的年龄依赖性

LeVine, Harry 3rd; Spielmann, H Peter; Matveev, Sergey; Cauvi, Francesca Macchiavello; Murphy, M Paul; Beckett, Tina L; McCarty, Katie; Lott, Ira T; Doran, Eric; Schmitt, Frederick; Head, Elizabeth

Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer's disease agents

β-咔啉类化合物的合成及其作为新型多功能抗阿尔茨海默病药物的应用

Horton, William; Sood, Abha; Peerannawar, Swarada; Kugyela, Nandor; Kulkarni, Aditya; Tulsan, Rekha; Tran, Chris D; Soule, Jessica; LeVine, Harry 3rd; Török, Béla; Török, Marianna

Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway

Aβ40通过泛素-蛋白酶体途径降低血脑屏障处的P-糖蛋白水平

Hartz, Anika M S; Zhong, Yu; Wolf, Andrea; LeVine, Harry 3rd; Miller, David S; Bauer, Björn

What amyloid ligands can tell us about molecular polymorphism and disease

淀粉样蛋白配体能告诉我们哪些关于分子多态性和疾病的信息

LeVine, Harry 3rd; Walker, Lary C

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

针对β淀粉样蛋白1-42寡聚体的阿尔茨海默病疗法II:Sigma-2/PGRMC1受体介导Aβ42寡聚体结合和突触毒性

Izzo, Nicholas J; Xu, Jinbin; Zeng, Chenbo; Kirk, Molly J; Mozzoni, Kelsie; Silky, Colleen; Rehak, Courtney; Yurko, Raymond; Look, Gary; Rishton, Gilbert; Safferstein, Hank; Cruchaga, Carlos; Goate, Alison; Cahill, Michael A; Arancio, Ottavio; Mach, Robert H; Craven, Rolf; Head, Elizabeth; LeVine, Harry 3rd; Spires-Jones, Tara L; Catalano, Susan M

Tritium-labeled (E,E)-2,5-bis(4'-hydroxy-3'-carboxystyryl)benzene as a probe for β-amyloid fibrils

氚标记的(E,E)-2,5-双(4'-羟基-3'-羧基苯乙烯基)苯作为β-淀粉样蛋白原纤维的探针

Matveev, Sergey V; Kwiatkowski, Stefan; Sviripa, Vitaliy M; Fazio, Robert C; Watt, David S; LeVine, Harry 3rd

Design, synthesis and biological activity of multifunctional α,β-unsaturated carbonyl scaffolds for Alzheimer's disease

多功能α,β-不饱和羰基骨架的设计、合成及其在阿尔茨海默病中的生物活性

Bag, Seema; Ghosh, Sanjukta; Tulsan, Rekha; Sood, Abha; Zhou, Weihong; Schifone, Christine; Foster, Michelle; LeVine, Harry 3rd; Török, Béla; Török, Marianna

Pittsburgh compound B and the postmortem diagnosis of Alzheimer disease

匹兹堡化合物B与阿尔茨海默病的尸检诊断

Niedowicz, Dana M; Beckett, Tina L; Matveev, Sergey; Weidner, Adam M; Baig, Irfan; Kryscio, Richard J; Mendiondo, Marta S; LeVine, Harry 3rd; Keller, Jeffrey N; Murphy, M Paul