日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells

更正：利用靶向受体的纳米颗粒对CFTR进行腺嘌呤碱基编辑可恢复G542X囊性纤维化气道上皮细胞的功能。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-06050-8
Rose, Isabelle; Greenwood, Miriam; Biggart, Matthew; Baumlin, Natalie; Tarran, Robert; Hart, Stephen L; Baines, Deborah L
信号转导
细胞生物学
碱基编辑
CFTR
上皮细胞
发表日期：2026
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Correction: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells

更正：利用靶向受体的纳米颗粒对CFTR进行腺嘌呤碱基编辑可恢复G542X囊性纤维化气道上皮细胞的功能。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-05907-2
Rose, Isabelle; Greenwood, Miriam; Biggart, Matthew; Baumlin, Natalie; Tarran, Robert; Hart, Stephen L; Baines, Deborah L
信号转导
细胞生物学
碱基编辑
CFTR
上皮细胞
发表日期：2025
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Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells

利用靶向受体的纳米颗粒对CFTR进行腺嘌呤碱基编辑，可恢复G542X囊性纤维化气道上皮细胞的功能。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-05587-y
Rose, Isabelle; Greenwood, Miriam; Biggart, Matthew; Baumlin, Natalie; Tarran, Robert; Hart, Stephen L; Baines, Deborah L
CFTR
上皮细胞
信号转导
碱基编辑
细胞生物学
发表日期：2025
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Delivering the Message: Translating mRNA Therapy for Liver Inherited Metabolic Diseases

传递信息：转化mRNA疗法治疗肝脏遗传性代谢疾病

期刊:Journal of Inherited Metabolic Disease
影响因子:3.8
doi:10.1002/jimd.70078
Gurung, Sonam; Perocheau, Dany; Ghosh, Roopkatha; Hart, Stephen L; Baruteau, Julien
代谢
发表日期：2025
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Characterisation of a primary ciliary dyskinesia model generated from BMI1-transduced basal epithelial cells.

对由 BMI1 转导的基底上皮细胞生成的原发性纤毛运动障碍模型进行表征。

期刊:Journal of Cell Science
影响因子:3.6
doi:10.1242/jcs.263886
Dalbay Melis T, Shahaj Eriomina, Guerrini Ileana, Lee Dani Do Hyang, Straatman-Iwanowska Anna, Mitchison Hannah M, Baines Deborah L, Hirst Robert A, Hogg Claire, O'Callaghan Christopher, Hart Stephen L
细胞生物学
上皮细胞
Bmi1
发表日期：2025
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In vitro platform to model the function of ionocytes in the human airway epithelium

用于模拟人呼吸道上皮细胞中离子细胞功能的体外平台

期刊:Respiratory Research
影响因子:5
doi:10.1186/s12931-024-02800-7
Vilà-González, Marta; Pinte, Laetitia; Fradique, Ricardo; Causa, Erika; Kool, Heleen; Rodrat, Mayuree; Morell, Carola Maria; Al-Thani, Maha; Porter, Linsey; Guo, Wenrui; Maeshima, Ruhina; Hart, Stephen L; McCaughan, Frank; Granata, Alessandra; Sheppard, David N; Floto, R Andres; Rawlins, Emma L; Cicuta, Pietro; Vallier, Ludovic
上皮细胞
细胞生物学
发表日期：2024
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Higher throughput drug screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia

针对罕见呼吸系统疾病的高通量药物筛选：原发性纤毛运动障碍的读通疗法

期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.00455-2020
Lee, Dani Do Hyang; Cardinale, Daniela; Nigro, Ersilia; Butler, Colin R; Rutman, Andrew; Fassad, Mahmoud R; Hirst, Robert A; Moulding, Dale; Agrotis, Alexander; Forsythe, Elisabeth; Peckham, Daniel; Robson, Evie; Smith, Claire M; Somavarapu, Satyanarayana; Beales, Philip L; Hart, Stephen L; Janes, Sam M; Mitchison, Hannah M; Ketteler, Robin; Hynds, Robert E; O'Callaghan, Christopher
呼吸系统疾病
发表日期：2021
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MYCN Silencing by RNAi Induces Neurogenesis and Suppresses Proliferation in Models of Neuroblastoma with Resistance to Retinoic Acid

RNAi介导的MYCN沉默可诱导神经发生并抑制对维甲酸耐药的神经母细胞瘤模型中的细胞增殖

期刊:Nucleic Acid Therapeutics
影响因子:4.7
doi:10.1089/nat.2019.0831
Maeshima, Ruhina; Moulding, Dale; Stoker, Andrew W; Hart, Stephen L
细胞生物学
MYC
发表日期：2020
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The discovery and enhanced properties of trichain lipids in lipopolyplex gene delivery systems

脂质体复合物基因递送系统中三链脂质的发现及其增强特性

期刊:Organic & Biomolecular Chemistry
影响因子:2.7
doi:10.1039/c8ob02374c
Mohammadi, Atefeh; Kudsiova, Laila; Mustapa, M Firouz Mohd; Campbell, Frederick; Vlaho, Danielle; Welser, Katharina; Story, Harriet; Tagalakis, Aristides D; Hart, Stephen L; Barlow, David J; Tabor, Alethea B; Lawrence, M Jayne; Hailes, Helen C
发表日期：2019
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BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity

BMI-1可延长人支气管上皮细胞的增殖潜能，同时保留其黏液纤毛分化能力。

期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology
影响因子:3.5
doi:10.1152/ajplung.00471.2016
Munye, Mustafa M; Shoemark, Amelia; Hirst, Robert A; Delhove, Juliette M; Sharp, Tyson V; McKay, Tristan R; O'Callaghan, Christopher; Baines, Deborah L; Howe, Steven J; Hart, Stephen L
上皮细胞
细胞生物学
发表日期：2017
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