日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Phase II Study of Potentiation of Pembrolizumab with Binimetinib and Bevacizumab in Refractory Microsatellite-Stable Colorectal Cancer

一项评估帕博利珠单抗联合比美替尼和贝伐珠单抗增强治疗难治性微卫星稳定型结直肠癌的II期研究

Lentz, Robert W; Friedrich, Tyler J; Blatchford, Patrick J; Jordan, Kimberly R; Pitts, Todd M; Robinson, Hannah R; Davis, S Lindsey; Kim, Sunnie S; Leal, Alexis D; Lee, Mathew R; Waring, Meredith R N; Martin, Anne C; Dominguez, Adrian T A; Bagby, Stacey M; Hartman, Sarah J; Eckhardt, S Gail; Messersmith, Wells A; Lieu, Christopher H

Expanding the landscape of oncogenic drivers and treatment options in acral and mucosal melanomas by targeted genomic profiling

通过靶向基因组分析拓展肢端和黏膜黑色素瘤致癌驱动因素和治疗选择的范围

Turner, Jacqueline A; Van Gulick, Robert J; Robinson, William A; Mughal, Tariq; Tobin, Richard P; MacBeth, Morgan L; Holman, Blair; Classon, Anthony; Bagby, Stacey M; Yacob, Betelehem W; Hartman, Sarah J; Silverman, Ian; Vorwald, Victoria M; Gorden, Nicholas; Gonzalez, Rita; Gay, Laurie M; Ali, Siraj M; Benson, Adam; Miller, Vincent A; Ross, Jeffrey S; Pitts, Todd M; Rioth, Matthew J; Lewis, Karl D; Medina, Theresa; McCarter, Martin D; Gonzalez, Rene; Couts, Kasey L

Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL).

利用胰腺肿瘤类器官库(PTOL)研究Wnt信号通路作为胰腺导管腺癌(PDAC)治疗靶点的作用

Hawkins Hayley J, Yacob Betelehem W, Brown Monica E, Goldstein Brandon R, Arcaroli John J, Bagby Stacey M, Hartman Sarah J, Macbeth Morgan, Goodspeed Andrew, Danhorn Thomas, Lentz Robert W, Lieu Christopher H, Leal Alexis D, Messersmith Wells A, Dempsey Peter J, Pitts Todd M

Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors

用于治疗实体瘤的I类选择性组蛋白去乙酰化酶抑制剂OKI-179的临床前开发

Diamond, Jennifer R; Pitts, Todd M; Ungermannova, Dana; Nasveschuk, Christopher G; Zhang, Gan; Phillips, Andrew J; Bagby, Stacey M; Pafford, Jessica; Yacob, Betelehem W; Newton, Timothy P; Tentler, John J; Gittleman, Brian; Hartman, Sarah J; DeMattei, John A; Winkler, James D; Wendt, Michael K; Schiemann, William P; Eckhardt, S Gail; Liu, Xuedong; Piscopio, Anthony D

ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer

ATM激酶抑制剂AZD0156联合伊立替康和5-氟尿嘧啶治疗结直肠癌的临床前模型

Davis, S Lindsey; Hartman, Sarah J; Bagby, Stacey M; Schlaepfer, Marina; Yacob, Betelehem W; Tse, Tonia; Simmons, Dennis M; Diamond, Jennifer R; Lieu, Christopher H; Leal, Alexis D; Cadogan, Elaine B; Hughes, Gareth D; Durant, Stephen T; Messersmith, Wells A; Pitts, Todd M

WEE1 Inhibition in Combination With Targeted Agents and Standard Chemotherapy in Preclinical Models of Pancreatic Ductal Adenocarcinoma

在胰腺导管腺癌的临床前模型中,WEE1抑制剂联合靶向药物和标准化疗的疗效

Hartman, Sarah J; Bagby, Stacey M; Yacob, Betelehem W; Simmons, Dennis M; MacBeth, Morgan; Lieu, Christopher H; Davis, S Lindsey; Leal, Alexis D; Tentler, John J; Diamond, Jennifer R; Eckhardt, S Gail; Messersmith, Wells A; Pitts, Todd M

Investigating the effects of a novel rumen-protected folic acid supplement on feedlot performance and carcass characteristics of beef steers

研究一种新型瘤胃保护型叶酸补充剂对肉牛育肥性能和胴体特性的影响

Deters, Erin L; Niedermayer, Emma K; Genther-Schroeder, Olivia N; Blank, Christopher P; Carmichael, Remy N; Hartman, Sarah J; Messersmith, Elizabeth M; VanValin, Katherine R; Branine, Mark E; Hansen, Stephanie L

RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

RX-5902 是一种新型 β-catenin 调节剂,可增强免疫检查点抑制剂在三阴性乳腺癌临床前模型中的疗效。

Tentler, John J; Lang, Julie; Capasso, Anna; Kim, Deog Joong; Benaim, Ely; Lee, Young B; Eisen, Andrew; Bagby, Stacey M; Hartman, Sarah J; Yacob, Betelehem W; Gittleman, Brian; Pitts, Todd M; Pelanda, Roberta; Eckhardt, S Gail; Diamond, Jennifer R

First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer

首创的磷酸化p68抑制剂RX-5902抑制β-catenin信号通路,并在三阴性乳腺癌中展现抗肿瘤活性

Capasso, Anna; Bagby, Stacey M; Dailey, Kyrie L; Currimjee, Naomi; Yacob, Betelehem W; Ionkina, Anastasia; Frank, Julie G; Kim, Deog Joong; George, Christina; Lee, Young B; Benaim, Ely; Gittleman, Brian; Hartman, Sarah J; Tan, Aik Choon; Kim, Jihye; Pitts, Todd M; Eckhardt, S Gail; Tentler, John J; Diamond, Jennifer R

The influence of supplemental zinc and ractopamine hydrochloride on trace mineral and nitrogen retention of beef steers

补充锌和盐酸莱克多巴胺对肉牛微量元素和氮保留的影响

Carmichael, Remy N; Genther-Schroeder, Olivia N; Blank, Christopher P; Deters, Erin L; Hartman, Sarah J; Niedermayer, Emma K; Hansen, Stephanie L