日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Progesterone receptor-dependent downregulation of MHC class I promotes tumor immune evasion and growth in breast cancer.

孕激素受体依赖性MHC I类分子下调促进乳腺癌肿瘤的免疫逃逸和生长

Tinoco Julio C, Saunders Harmony I, Werner Lauryn Rose, Sun Xiaopeng, Chowanec Eilidh I, Heard Amanda, Chalise Prabhakar, Vahrenkamp Jeffery M, Wilson Andrea E, Liu Cong-Xiao, Lei Gangjun, Wei Junping, Cros Hugo, Mohammed Hisham, Troester Melissa, Perou Charles, Markiewicz Mary A, Gertz Jason, Balko Justin M, Hartman Zachary Conrad, Hagan Christy R

Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers

新型靶向热休克蛋白90的光动力疗法与PD-1/PD-L1阻断疗法相结合,可诱导强效的全身抗肿瘤疗效和对乳腺癌的远隔效应。

Kaneko, Kensuke; Acharya, Chaitanya R; Nagata, Hiroshi; Yang, Xiao; Hartman, Zachary Conrad; Hobeika, Amy; Hughes, Philip F; Haystead, Timothy A J; Morse, Michael A; Lyerly, Herbert Kim; Osada, Takuya

HER2-LAMP vaccines effectively traffic to endolysosomal compartments and generate enhanced polyfunctional T cell responses that induce complete tumor regression

HER2-LAMP疫苗能有效转运至内溶酶体区室,并产生增强的多功能T细胞反应,从而诱导肿瘤完全消退。

Chen, Alan Chen; Xu, Renhuan; Wang, Tao; Wei, Junping; Yang, Xiao-Yi; Liu, Cong-Xiao; Lei, Gangjun; Lyerly, Herbert Kim; Heiland, Teri; Hartman, Zachary Conrad