日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21

发现并表征 BAY-805,一种强效且选择性的泛素特异性蛋白酶 USP21 抑制剂

Fabian Göricke, Victoria Vu, Leanna Smith, Ulrike Scheib, Raphael Böhm, Namik Akkilic, Gerd Wohlfahrt, Jörg Weiske, Ulf Bömer, Krzysztof Brzezinka, Niels Lindner, Philip Lienau, Stefan Gradl, Hartmut Beck, Peter J Brown, Vijayaratnam Santhakumar, Masoud Vedadi, Dalia Barsyte-Lovejoy, Cheryl H Arrows

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I

BAY 87-2243 是一种高效且选择性的缺氧诱导基因激活抑制剂,通过抑制线粒体复合物 I 发挥抗肿瘤活性

Peter Ellinghaus, Iring Heisler, Kerstin Unterschemmann, Michael Haerter, Hartmut Beck, Susanne Greschat, Alexander Ehrmann, Holger Summer, Ingo Flamme, Felix Oehme, Karlheinz Thierauch, Martin Michels, Holger Hess-Stumpp, Karl Ziegelbauer