日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Profilin 1-mediated cytoskeletal rearrangements regulate integrin function in mouse platelets

Profilin 1介导的细胞骨架重排调节小鼠血小板中的整合素功能

Stritt, Simon; Birkholz, Inga; Beck, Sarah; Sorrentino, Simona; Sapra, K Tanuj; Viaud, Julien; Heck, Johannes; Gaits-Iacovoni, Frédérique; Schulze, Harald; Du, Xiaoping; Hartwig, John H; Braun, Attila; Bender, Markus; Medalia, Ohad; Nieswandt, Bernhard

Sarcomeric and nonmuscle α-actinin isoforms exhibit differential dynamics at skeletal muscle Z-lines

肌节和非肌肉α-辅肌动蛋白同工型在骨骼肌Z线处表现出不同的动力学特征

Hsu, Cynthia P; Moghadaszadeh, Behzad; Hartwig, John H; Beggs, Alan H

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation

巨核细胞成熟后期MARCKS的合成和去磷酸化驱动前血小板的形成。

Machlus, Kellie R; Wu, Stephen K; Stumpo, Deborah J; Soussou, Thomas S; Paul, David S; Campbell, Robert A; Kalwa, Hermann; Michel, Thomas; Bergmeier, Wolfgang; Weyrich, Andrew S; Blackshear, Perry J; Hartwig, John H; Italiano, Joseph E Jr

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.

Ashwell-Morell 受体通过 JAK2-STAT3 信号通路调节肝脏血小板生成素的产生

Grozovsky Renata, Begonja Antonija Jurak, Liu Kaifeng, Visner Gary, Hartwig John H, Falet Hervé, Hoffmeister Karin M

Wiskott-Aldrich syndrome protein (WASp) controls the delivery of platelet transforming growth factor-β1

Wiskott-Aldrich综合征蛋白(WASp)控制血小板转化生长因子-β1的递送

Kim, Hugh; Falet, Hervé; Hoffmeister, Karin M; Hartwig, John H

Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion

profilin亚型对肌动蛋白细胞骨架结构的差异性重塑导致对细胞迁移和侵袭的不同影响。

Mouneimne, Ghassan; Hansen, Scott D; Selfors, Laura M; Petrak, Lara; Hickey, Michele M; Gallegos, Lisa L; Simpson, Kaylene J; Lim, James; Gertler, Frank B; Hartwig, John H; Mullins, R Dyche; Brugge, Joan S

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice

去唾液酸化作用可加速冷藏后血小板的清除,并启动小鼠体内GPIbα金属蛋白酶介导的裂解。

Jansen, A J Gerard; Josefsson, Emma C; Rumjantseva, Viktoria; Liu, Qiyong Peter; Falet, Hervé; Bergmeier, Wolfgang; Cifuni, Stephen M; Sackstein, Robert; von Andrian, Ulrich H; Wagner, Denisa D; Hartwig, John H; Hoffmeister, Karin M

Electron microscopy and 3D reconstruction reveals filamin Ig domain binding to F-actin

电子显微镜和三维重建揭示了丝状蛋白Ig结构域与F-肌动蛋白的结合

Suphamungmee, Worawit; Nakamura, Fumihiko; Hartwig, John H; Lehman, William

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

基于血影蛋白的膜骨架能够稳定小鼠巨核细胞膜系统,并且对前血小板和血小板的形成至关重要。

Patel-Hett, Sunita; Wang, Hongbei; Begonja, Antonija J; Thon, Jonathan N; Alden, Eva C; Wandersee, Nancy J; An, Xiuli; Mohandas, Narla; Hartwig, John H; Italiano, Joseph E Jr

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

FlnA基因缺失的巨核细胞会过早释放体积大、质地脆弱、循环能力差的血小板。

Jurak Begonja, Antonija; Hoffmeister, Karin M; Hartwig, John H; Falet, Hervé