日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A novel extracellular flux assay workflow uncovers impaired sciatic nerve mitochondrial respiration in diabetic db/db mice

一种新型的细胞外通量检测方法揭示了糖尿病db/db小鼠坐骨神经线粒体呼吸功能受损。

期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-026-02667-9
Sill, Sebastian; Ouwens, D Margriet; Zivehe, Fariba; Hartwig, Sonja; Lehr, Stefan; Bönhof, Gidon J; Roden, Michael; Al-Hasani, Hadi; Chadt, Alexandra; Strom, Alexander
糖尿病
细胞生物学
线粒体
代谢
发表日期：2026
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A single-cell derived spheroid approach to dissect intratumoural heterogeneity in colorectal cancer: cell lines show changes in proteomes and therapeutic response to 5-FU

利用单细胞衍生球体方法解析结直肠癌肿瘤内异质性：细胞系显示蛋白质组变化及对5-氟尿嘧啶的治疗反应

期刊:Journal of Cancer Research and Clinical Oncology
影响因子:2.8
doi:10.1007/s00432-025-06418-0
Radloff, Helene Sophia; Kohl, Michael; Sauer, Thorben; Hartwig, Sonja; Geisler, Sven; Lehr, Stefan; Gemoll, Timo
肿瘤
肠癌
肿瘤免疫
细胞生物学
单细胞
发表日期：2026
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High-resolution analyses of the secretomes from murine C2C12 cells and primary human skeletal muscle cells reveal distinct differences in contraction-regulated myokine secretion.

对小鼠 C2C12 细胞和原代人类骨骼肌细胞的分泌组进行高分辨率分析，揭示了收缩调节肌细胞因子分泌的明显差异

期刊:Frontiers in Physiology
影响因子:3.4
doi:10.3389/fphys.2025.1549316
Förster Pia Marlene, Hogenkamp Julian, Pottgießer Moira Fee, Binsch Christian, Humpert Awovi Didi, Brügge Carolin Laura, Deatc Michelle Isabel, Ensenauer Regina, Chadt Alexandra, Thoresen G Hege, Ouwens D Margriet, Hartwig Sonja, Lehr Stefan, Al-Hasani Hadi
细胞生物学
Human
发表日期：2025
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The role of exosomes for sustained specific cardiorespiratory and metabolic improvements in males with type 2 diabetes after detraining

外泌体在2型糖尿病男性停止训练后持续改善特定心肺和代谢功能中的作用

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2024.105471
Mastrototaro, Lucia; Apostolopoulou, Maria; Hartwig, Sonja; Strassburger, Klaus; Lipaeva, Polina; Trinks, Nina; Karusheva, Yanislava; Gancheva, Sofiya; Trenkamp, Sandra; Lehr, Stefan; Al-Hasani, Hadi; Szendroedi, Julia; Roden, Michael
糖尿病
外泌体
代谢
发表日期：2024
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Correction: Gemoll et al. Protein Profiling of Serum Extracellular Vesicles Reveals Qualitative and Quantitative Differences after Differential Ultracentrifugation and ExoQuick™ Isolation. J. Clin. Med. 2020, 9, 1429

更正：Gemoll 等人，《血清细胞外囊泡的蛋白质谱分析揭示了差速超速离心和 ExoQuick™ 分离后的定性和定量差异》，《临床医学杂志》，2020 年，9，1429。

期刊:Journal of Clinical Medicine
影响因子:2.9
doi:10.3390/jcm10153343
Gemoll, Timo; Strohkamp, Sarah; Rozanova, Svitlana; Röder, Christian; Hartwig, Sonja; Kalthoff, Holger; Lehr, Stefan; ElSharawy, Abdou; Habermann, Jens K
囊泡
细胞生物学
发表日期：2021
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Protein Profiling of Serum Extracellular Vesicles Reveals Qualitative and Quantitative Differences After Differential Ultracentrifugation and ExoQuick(TM) Isolation

血清细胞外囊泡的蛋白质谱分析揭示了差速超速离心和ExoQuick(TM)分离后的定性和定量差异

期刊:Journal of Clinical Medicine
影响因子:2.9
doi:10.3390/jcm9051429
Gemoll, Timo; Rozanova, Svitlana; Röder, Christian; Hartwig, Sonja; Kalthoff, Holger; Lehr, Stefan; ElSharawy, Abdou; Habermann, Jens K
囊泡
细胞生物学
发表日期：2020
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Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition

肥胖小鼠模型中的脂肪因子组特征反映了脂肪组织健康状况，并与血清脂质组成相关。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms20102559
Knebel, Birgit; Fahlbusch, Pia; Poschmann, Gereon; Dille, Matthias; Wahlers, Natalie; Stühler, Kai; Hartwig, Sonja; Lehr, Stefan; Schiller, Martina; Jacob, Sylvia; Kettel, Ulrike; Müller-Wieland, Dirk; Kotzka, Jörg
肥胖
Mouse
代谢
发表日期：2019
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Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes

SREBP-1a磷酸化失活可预防小鼠脂肪肝：通过肝脏基因表达谱和过氧化物酶体蛋白质组学鉴定相关信号通路

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms19040980
Knebel, Birgit; Hartwig, Sonja; Jacob, Sylvia; Kettel, Ulrike; Schiller, Martina; Passlack, Waltraud; Koellmer, Cornelia; Lehr, Stefan; Müller-Wieland, Dirk; Kotzka, Jorg
信号转导
EBP
代谢
脂肪肝
磷酸化
发表日期：2018
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AKT and AMP-activated protein kinase regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP

AKT 和 AMP 激活蛋白激酶通过磷酸化及其与胰岛素调节氨肽酶 IRAP 胞质尾部的相互作用来调节 TBC1D1。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.005040
Mafakheri, Samaneh; Flörke, Ralf R; Kanngießer, Sibylle; Hartwig, Sonja; Espelage, Lena; De Wendt, Christian; Schönberger, Tina; Hamker, Nele; Lehr, Stefan; Chadt, Alexandra; Al-Hasani, Hadi
免疫/内分泌
信号转导
AKT
磷酸化
发表日期：2018
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Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models

肥胖及肥胖/糖尿病小鼠模型脂肪因子组的新见解

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms18091928
Knebel, Birgit; Goeddeke, Simon; Poschmann, Gereon; Markgraf, Daniel F; Jacob, Sylvia; Nitzgen, Ulrike; Passlack, Waltraud; Preuss, Christina; Dicken, Hans-Dieter; Stühler, Kai; Hartwig, Sonja; Lehr, Stefan; Kotzka, Jorg
Mouse
发表日期：2017
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