日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacological tools to modulate ordered membrane domains and order-dependent protein function

利用药理学工具调节有序膜结构域和有序依赖性蛋白质功能

Stefanski, Katherine M; Huang, Hui; Luu, Dustin D; Li, Geoffrey C; Hutchison, James M; Saksena, Nilabh; Fisch, Alexander J; Hasaka, Thomas P; Bauer, Joshua A; Kenworthy, Anne K; Van Horn, Wade D; Sanders, Charles R

High-throughput screening identifies a trafficking corrector for long QT syndrome-associated KCNQ1 variants

高通量筛选鉴定出一种与长QT综合征相关的KCNQ1变异体的转运校正因子

Moster, Katherine R Clowes; Vanoye, Carlos G; Chang-Gonzalez, Ana C; Romaine, Ian M; Stefanski, Katherine M; Wilkinson, Mason C; Bauer, Joshua A; Hasaka, Thomas P; Days, Emily L; Desai, Reshma R; Butcher, Kathryn R; Sulikowski, Gary A; Waterson, Alex G; Meiler, Jens; Ledwitch, Kaitlyn V; George, Alfred L Jr; Sanders, Charles R

Protocol for high-throughput drug screening in 384-well 3D collagen cultures of SC colorectal cancer cells using colony morphology as a readout

利用集落形态作为读数指标,在384孔3D胶原培养的SC结直肠癌细胞中进行高通量药物筛选的方案

Harmych, Sarah J; Hasaka, Thomas P; Jones, Vivian Truong; Bauer, Joshua A; Singh, Bhuminder

3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer.

3D胶原蛋白高通量筛选可识别诱导上皮极性并增强结直肠癌化疗反应的药物

Harmych Sarah J, Hasaka Thomas P, Sievers Chelsie K, Kang Seung Woo, Ramirez Marisol A, Jones Vivian Truong, Zhao Zhiguo, Kovtun Oleg, Wahoski Claudia C, Liu Qi, Lau Ken S, Coffey Robert J, Bauer Joshua A, Singh Bhuminder

High Throughput Screening Identifies a Small Molecule Trafficking Corrector for Long-QT Syndrome Associated KCNQ1 Variants

高通量筛选鉴定出一种针对长QT综合征相关KCNQ1变异的小分子转运校正剂

Moster, Katherine R Clowes; Vanoye, Carlos G; Chang-Gonzalez, Ana C; Romaine, Ian M; Stefanski, Katherine M; Wilkinson, Mason C; Bauer, Joshua A; Hasaka, Thomas P; Days, Emily L; Desai, Reshma R; Butcher, Kathryn R; Sulikowski, Gary A; Waterson, Alex G; Meiler, Jens; Ledwitch, Kaitlyn V; George, Alfred L Jr; Sanders, Charles R

Pharmacological Tools to Modulate Ordered Membrane Domains and Order-Dependent Protein Function

利用药理学工具调节有序膜结构域和有序依赖性蛋白质功能

Stefanski, Katherine M; Huang, Hui; Luu, Dustin D; Hutchison, James M; Saksena, Nilabh; Fisch, Alexander J; Hasaka, Thomas P; Bauer, Joshua A; Kenworthy, Anne K; Van Horn, Wade D; Sanders, Charles R

Small-Molecule Modulators of Lipid Raft Stability and Protein-Raft Partitioning

脂筏稳定性和蛋白质筏分配的小分子调节剂

Katherine M Stefanski, Hui Huang, Dustin D Luu, James M Hutchison, Nilabh Saksena, Alexander J Fisch, Thomas P Hasaka, Joshua A Bauer, Anne K Kenworthy, Wade D Van Horn, Charles R Sanders

A High-Throughput Immune-Oncology Screen Identifies Immunostimulatory Properties of Cytotoxic Chemotherapy Agents in TNBC

高通量免疫肿瘤学筛选确定了 TNBC 中细胞毒性化疗药物的免疫刺激特性

Kennady K Bullock, Thomas Hasaka, Emily Days, Joshua A Bauer, Patricia A Ward, Ann Richmond

The Potential of Digested Sludge-Assimilating Microflora for Biogas Production from Food Processing Wastes

利用消化污泥同化微生物群从食品加工废弃物中生产沼气的潜力

Hasaka, Sato; Sakamoto, Saki; Fujii, Katsuhiko

Deep Learning-Based HCS Image Analysis for the Enterprise

面向企业的基于深度学习的HCS图像分析

Steigele, Stephan; Siegismund, Daniel; Fassler, Matthias; Kustec, Marusa; Kappler, Bernd; Hasaka, Tom; Yee, Ada; Brodte, Annette; Heyse, Stephan