日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Pharmacological tools to modulate ordered membrane domains and order-dependent protein function

利用药理学工具调节有序膜结构域和有序依赖性蛋白质功能

期刊:Communications Chemistry
影响因子:6.2
doi:10.1038/s42004-025-01874-8
Stefanski, Katherine M; Huang, Hui; Luu, Dustin D; Li, Geoffrey C; Hutchison, James M; Saksena, Nilabh; Fisch, Alexander J; Hasaka, Thomas P; Bauer, Joshua A; Kenworthy, Anne K; Van Horn, Wade D; Sanders, Charles R
发表日期：2026
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High-throughput screening identifies a trafficking corrector for long QT syndrome-associated KCNQ1 variants

高通量筛选鉴定出一种与长QT综合征相关的KCNQ1变异体的转运校正因子

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.201297
Moster, Katherine R Clowes; Vanoye, Carlos G; Chang-Gonzalez, Ana C; Romaine, Ian M; Stefanski, Katherine M; Wilkinson, Mason C; Bauer, Joshua A; Hasaka, Thomas P; Days, Emily L; Desai, Reshma R; Butcher, Kathryn R; Sulikowski, Gary A; Waterson, Alex G; Meiler, Jens; Ledwitch, Kaitlyn V; George, Alfred L Jr; Sanders, Charles R
发表日期：2026
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Protocol for high-throughput drug screening in 384-well 3D collagen cultures of SC colorectal cancer cells using colony morphology as a readout

利用集落形态作为读数指标，在384孔3D胶原培养的SC结直肠癌细胞中进行高通量药物筛选的方案

期刊:STAR Protocols
影响因子:1.3
doi:10.1016/j.xpro.2025.104300
Harmych, Sarah J; Hasaka, Thomas P; Jones, Vivian Truong; Bauer, Joshua A; Singh, Bhuminder
肿瘤
肠癌
肿瘤免疫
3D/类器官
细胞生物学
发表日期：2026
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3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer.

3D胶原蛋白高通量筛选可识别诱导上皮极性并增强结直肠癌化疗反应的药物

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08699-0
Harmych Sarah J, Hasaka Thomas P, Sievers Chelsie K, Kang Seung Woo, Ramirez Marisol A, Jones Vivian Truong, Zhao Zhiguo, Kovtun Oleg, Wahoski Claudia C, Liu Qi, Lau Ken S, Coffey Robert J, Bauer Joshua A, Singh Bhuminder
肿瘤
肠癌
肿瘤免疫
发表日期：2025
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High Throughput Screening Identifies a Small Molecule Trafficking Corrector for Long-QT Syndrome Associated KCNQ1 Variants

高通量筛选鉴定出一种针对长QT综合征相关KCNQ1变异的小分子转运校正剂

期刊:
影响因子:
doi:10.1101/2025.10.13.682066
Moster, Katherine R Clowes; Vanoye, Carlos G; Chang-Gonzalez, Ana C; Romaine, Ian M; Stefanski, Katherine M; Wilkinson, Mason C; Bauer, Joshua A; Hasaka, Thomas P; Days, Emily L; Desai, Reshma R; Butcher, Kathryn R; Sulikowski, Gary A; Waterson, Alex G; Meiler, Jens; Ledwitch, Kaitlyn V; George, Alfred L Jr; Sanders, Charles R
发表日期：2025
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Pharmacological Tools to Modulate Ordered Membrane Domains and Order-Dependent Protein Function

利用药理学工具调节有序膜结构域和有序依赖性蛋白质功能

期刊:
影响因子:
doi:10.1101/2025.10.03.680351
Stefanski, Katherine M; Huang, Hui; Luu, Dustin D; Hutchison, James M; Saksena, Nilabh; Fisch, Alexander J; Hasaka, Thomas P; Bauer, Joshua A; Kenworthy, Anne K; Van Horn, Wade D; Sanders, Charles R
发表日期：2025
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A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay

利用细胞染色分析法，构建了一个包含30000个小分子处理样本的图像和形态学特征的数据集。

期刊:Gigascience
影响因子:3.9
doi:10.1093/gigascience/giw014
Bray, Mark-Anthony; Gustafsdottir, Sigrun M; Rohban, Mohammad H; Singh, Shantanu; Ljosa, Vebjorn; Sokolnicki, Katherine L; Bittker, Joshua A; Bodycombe, Nicole E; Dancík, Vlado; Hasaka, Thomas P; Hon, Cindy S; Kemp, Melissa M; Li, Kejie; Walpita, Deepika; Wawer, Mathias J; Golub, Todd R; Schreiber, Stuart L; Clemons, Paul A; Shamji, Alykhan F; Carpenter, Anne E
细胞生物学
发表日期：2017
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