日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The cotranslational cycle of the ribosome-bound Hsp70 homolog Ssb

核糖体结合的Hsp70同源物Ssb的共翻译循环

Zhang, Ying; Grundmann, Lorenz; Vollmar, Leonie; Schimpf, Julia; Hübscher, Volker; Areeb, Mohd; Grishkovskaya, Irina; Moddemann, Anna; Werner, Kerstin; Hugel, Thorsten; Haselbach, David; Rospert, Sabine

A multivalent adaptor mechanism drives the nuclear import of proteasomes

多价衔接蛋白机制驱动蛋白酶体的核输入

Brunner, Hanna L; Kalis, Robert W; Grundmann, Lorenz; Hodáková, Zuzana; Koskova, Zuzana; Grishkovskaya, Irina; de Almeida, Melanie; Hinterndorfer, Matthias; Knaudt, Hannah; Höfflin, Simon; Andersch, Florian; Kotisch, Harald; Dickmanns, Achim; Cuylen-Haering, Sara; Zuber, Johannes; Haselbach, David

Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity

守护者泛素E3连接酶靶向癌症相关的APOBEC3脱氨酶进行降解,从而促进人类基因组的完整性。

Schwartz, Irene; Budroni, Valentina; Meyenberg, Mathilde; Hodakova, Zuzana; Hornegger, Harald; Hacker, Kathrin; Schwartz, Siegfried; Grabarczyk, Daniel B; Ehrmann, Julian F; Scinicariello, Sara; Haselbach, David; Menche, Jörg; Clausen, Tim; Karagöz, G Elif; Versteeg, Gijs A

Electrostatic changes enabled the diversification of an exocyst subunit via protein complex escape

静电变化使得胞吐复合体亚基能够通过蛋白质复合物逃逸而发生多样化。

De la Concepcion, Juan Carlos; Duverge, Héloïse; Kim, Yoonwoo; Julian, Jose; Xu, Haonan D; Watt, Matthew N; Ikene, Sara Ait; Bianchi, Anita; Grujic, Nenad; Papareddy, Ranjith K; Grishkovskaya, Irina; Haselbach, David; Murray, David H; Clavel, Marion; Irwin, Nicholas A T; Dagdas, Yasin

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22.

通过靶向募集 SCF-FBXO22 实现 NSD2 降解的结构基础

Robertson Kevin C, Amann Sascha J, Liu Tongkun, Funk Adam V, Wang Xianxi, Grishkovskaya Irina, Tabor John R, Norris-Drouin Jacqueline L, Arrowsmith Cheryl H, Collins Jon L, Emanuele Michael J, Haselbach David, James Lindsey I, Brown Nicholas Gene

The slow photo-induced CO2 release of N-phthaloylglycine

N-邻苯二甲酰甘氨酸缓慢光诱导释放 CO2

Wiebke Haselbach, Oliver Nolden, Nadine Blaise, Tom Förster, Mick Gindorf, Mathieu Kippes, Michelle P Rademacher, Matthias Jantz, Luuk J G W van Wilderen, Jens Bredenbeck, Josef Wachtveitl, Peter Gilch

A New Ex Vivo Human Skin Burn Model

一种新的离体人体皮肤烧伤模型

Labouchère, Ania; Haselbach, Daniel; Michetti, Murielle; Pythoud, Catherine; Raffoul, Wassim; Applegate, Lee Ann; Hirt-Burri, Nathalie; de Buys Roessingh, Anthony

A dual ribosomal system in the zebrafish soma and germline

斑马鱼体细胞和生殖细胞中的双核糖体系统

Arish N Shah, Friederike Leesch, Laura Lorenzo-Orts, Lorenz Grundmann, Maria Novatchkova, David Haselbach, Eliezer Calo, Andrea Pauli

A molecular network of conserved factors keeps ribosomes dormant in the egg

保守因子的分子网络使核糖体在卵子中处于休眠状态

Friederike Leesch #, Laura Lorenzo-Orts #, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli

Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C)

利用时间分辨冷冻电镜(TR-EM)分析 RING E3 后期促进复合物/细胞周期体(APC/C)对底物进行多聚泛素化

Bodrug, Tatyana; Welsh, Kaeli A; Bolhuis, Derek L; Paulаkonis, Ethan; Martinez-Chacin, Raquel C; Liu, Bei; Pinkin, Nicholas; Bonacci, Thomas; Cui, Liying; Xu, Pengning; Roscow, Olivia; Amann, Sascha Josef; Grishkovskaya, Irina; Emanuele, Michael J; Harrison, Joseph S; Steimel, Joshua P; Hahn, Klaus M; Zhang, Wei; Zhong, Ellen D; Haselbach, David; Brown, Nicholas G