Direct evidence of generation and accumulation of β-sheet-rich prion protein in scrapie-infected neuroblastoma cells with human IgG1 antibody specific for β-form prion protein
利用针对β型朊病毒蛋白的人类IgG1抗体，直接证实了在羊瘙痒病感染的神经母细胞瘤细胞中β折叠丰富的朊病毒蛋白的生成和积累。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M111.318352
Kubota, Toshiya; Hamazoe, Yuta; Hashiguchi, Shuhei; Ishibashi, Daisuke; Akasaka, Kazuyuki; Nishida, Noriyuki; Katamine, Shigeru; Sakaguchi, Suehiro; Kuroki, Ryota; Nakashima, Toshihiro; Sugimura, Kazuhisa
