日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

mRNA interactions with disordered regions control protein activity

mRNA与无序区域的相互作用控制蛋白质活性

Yang Luo, Supriya Pratihar, Ellen H Horste, Sibylle Mitschka, Antonia S J S Mey, Hashim M Al-Hashimi, Christine Mayr

RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs

RBM45是一种m6A结合蛋白,它影响神经元分化和部分mRNA的剪接。

Seung H Choi ,Mathieu N Flamand ,Bei Liu ,Huanyu Zhu ,Meghan Hu ,Melanie Wang ,Jonathon Sewell ,Christopher L Holley ,Hashim M Al-Hashimi ,Kate D Meyer

A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions

定量模型预测 m6A 如何重塑核酸杂交和构象转变的动力学格局

Bei Liu, Honglue Shi, Atul Rangadurai, Felix Nussbaumer, Chia-Chieh Chu, Kevin Andreas Erharter, David A Case, Christoph Kreutz, Hashim M Al-Hashimi

Modulation of Hoogsteen dynamics on DNA recognition

Hoogsteen 动力学对 DNA 识别的调节

Yu Xu, James McSally, Ioan Andricioaei, Hashim M Al-Hashimi

A potentially abundant junctional RNA motif stabilized by m6A and Mg2

由 m6A 和 Mg2 稳定的潜在丰富连接 RNA 基序

Bei Liu, Dawn K Merriman, Seung H Choi, Maria A Schumacher, Raphael Plangger, Christoph Kreutz, Stacy M Horner, Kate D Meyer, Hashim M Al-Hashimi

Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions

假尿苷和 N6-甲基腺苷修饰削弱了 PUF 蛋白/RNA 相互作用

Pavanapuresan P Vaidyanathan, Ishraq AlSadhan, Dawn K Merriman, Hashim M Al-Hashimi, Daniel Herschlag

m(1)A and m(1)G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs

m(1)A 和 m(1)G 通过 Hoogsteen 碱基对的固有不稳定性破坏 A-RNA 结构。

Huiqing Zhou,Isaac J Kimsey,Evgenia N Nikolova,Bharathwaj Sathyamoorthy,Gianmarc Grazioli,James McSally,Tianyu Bai,Christoph H Wunderlich,Christoph Kreutz,Ioan Andricioaei,Hashim M Al-Hashimi

Influence of dimethylsulfoxide on RNA structure and ligand binding

二甲基亚砜对 RNA 结构和配体结合的影响

Janghyun Lee, Catherine E Vogt, Mitchell McBrairty, Hashim M Al-Hashimi

Visualizing transient low-populated structures of RNA

可视化RNA的瞬时低密度结构

Elizabeth A Dethoff,Katja Petzold, Jeetender Chugh, Anette Casiano-Negroni, Hashim M Al-Hashimi

Transient Hoogsteen base pairs in canonical duplex DNA

典型双链 DNA 中的瞬时 Hoogsteen 碱基对

Evgenia N Nikolova, Eunae Kim, Abigail A Wise, Patrick J O'Brien, Ioan Andricioaei, Hashim M Al-Hashimi