Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity
IgG1抗体中电荷介导的Fab-Fc相互作用可诱导可逆的自缔合、聚集和黏度升高。
期刊:MAbs
影响因子:7.3
doi:10.1080/19420862.2016.1222342
Arora, Jayant; Hu, Yue; Esfandiary, Reza; Sathish, Hasige A; Bishop, Steven M; Joshi, Sangeeta B; Middaugh, C Russell; Volkin, David B; Weis, David D