日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prostate Cancer-Specific Lysine 53 Acetylation of Cytochrome c Drives Metabolic Reprogramming and Protects from Apoptosis in Intact Cells

前列腺癌特异性细胞色素c赖氨酸53乙酰化驱动代谢重编程并保护完整细胞免于凋亡

Paul T Morse ,Junmei Wan ,Tasnim Arroum ,Mackenzie K Herroon ,Hasini A Kalpage ,Viktoriia Bazylianska ,Icksoo Lee ,Elisabeth I Heath ,Izabela Podgorski ,Maik Hüttemann

Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle

细胞色素c赖氨酸乙酰化调节缺血性骨骼肌的细胞呼吸和细胞死亡

Paul T Morse # ,Gonzalo Pérez-Mejías # ,Junmei Wan ,Alice A Turner ,Inmaculada Márquez ,Hasini A Kalpage ,Asmita Vaishnav ,Matthew P Zurek ,Philipp P Huettemann ,Katherine Kim ,Tasnim Arroum ,Miguel A De la Rosa ,Dipanwita Dutta Chowdhury ,Icksoo Lee ,Joseph S Brunzelle ,Thomas H Sanderson ,Moh H Malek ,David Meierhofer ,Brian F P Edwards ,Irene Díaz-Moreno ,Maik Hüttemann

Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis

二甲双胍、苯乙双胍和加利根抑制复合物IV活性,从而降低甘油衍生的糖异生作用。

LaMoia, Traci E; Butrico, Gina M; Kalpage, Hasini A; Goedeke, Leigh; Hubbard, Brandon T; Vatner, Daniel F; Gaspar, Rafael C; Zhang, Xian-Man; Cline, Gary W; Nakahara, Keita; Woo, Seungwan; Shimada, Atsuhiro; Hüttemann, Maik; Shulman, Gerald I

Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia

HDAC、PI3K 和 Bcl-2 的共同靶向作用导致急性髓系白血病的代谢和转录重编程以及线粒体功能下降

Katie Hege Hurrish, Xinan Qiao, Xinyu Li, Yongwei Su, Jenna Carter, Jun Ma, Hasini A Kalpage, Maik Hüttemann, Holly Edwards, Guan Wang, Seongho Kim, Alan Dombkowski, Xun Bao, Jing Li, Jeffrey W Taub, Yubin Ge

Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis

前列腺癌中细胞色素 c 的赖氨酸 53 乙酰化:Warburg 代谢和细胞凋亡的逃避

Viktoriia Bazylianska, Hasini A Kalpage, Junmei Wan, Asmita Vaishnav, Gargi Mahapatra, Alice A Turner, Dipanwita Dutta Chowdhury, Katherine Kim, Paul T Morse, Icksoo Lee, Joseph S Brunzelle, Lisa Polin, Prabal Subedi, Elisabeth I Heath, Izabela Podgorski, Katrin Marcus, Brian F P Edwards, Maik Hütte

Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy

靶向多个信号通路:急性髓系白血病治疗的新方法

Carter, Jenna L; Hege, Katie; Yang, Jay; Kalpage, Hasini A; Su, Yongwei; Edwards, Holly; Hüttemann, Maik; Taub, Jeffrey W; Ge, Yubin

Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling

脑特异性丝氨酸-47修饰细胞色素c调节细胞色素c氧化酶活性,从而减弱ROS产生和细胞死亡:对缺血/再灌注损伤和Akt信号通路的影响

Hasini A Kalpage ,Junmei Wan ,Paul T Morse ,Icksoo Lee ,Maik Hüttemann

Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis

细胞色素c磷酸化:线粒体电子传递链通量和细胞凋亡的调控

Kalpage, Hasini A; Wan, Junmei; Morse, Paul T; Zurek, Matthew P; Turner, Alice A; Khobeir, Antoine; Yazdi, Nabil; Hakim, Lara; Liu, Jenney; Vaishnav, Asmita; Sanderson, Thomas H; Recanati, Maurice-Andre; Grossman, Lawrence I; Lee, Icksoo; Edwards, Brian F P; Hüttemann, Maik

Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation

线粒体复合物 I 和 Bcl-2 的共靶向作用对依赖氧化磷酸化的急性髓系白血病细胞表现出抗白血病活性

Fangbing Liu, Hasini A Kalpage, Deying Wang, Holly Edwards, Maik Hüttemann, Jun Ma, Yongwei Su, Jenna Carter, Xinyu Li, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Kathryn White, Guan Wang, Jeffrey W Taub, Yubin Ge

Serine-47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase-3 activity

哺乳动物大脑中细胞色素 c 的丝氨酸-47 磷酸化调节细胞色素 c 氧化酶和 caspase-3 活性

Hasini A Kalpage, Asmita Vaishnav, Jenney Liu, Ashwathy Varughese, Junmei Wan, Alice A Turner, Qinqin Ji, Matthew P Zurek, Alexandr A Kapralov, Valerian E Kagan, Joseph S Brunzelle, Maurice-Andre Recanati, Lawrence I Grossman, Thomas H Sanderson, Icksoo Lee, Arthur R Salomon, Brian F P Edwards, Maik