日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists

肽基甘氨酸α-酰胺化单加氧酶中的2型糖尿病风险等位基因会影响GLP-1水平和对GLP-1受体激动剂的反应。

Umapathysivam, Mahesh M; Araldi, Elisa; Hastoy, Benoit; Dawed, Adem Y; Vatandaslar, Hasan; Mayrhofer, Johanna E; Lindquist, Peter; Silva, Pamuditha N; Goga, Algera; Trüllinger, Geraldine O; Godbersen, Svenja; Sengupta, Shahana; Kaufmann, Adrian; Thomsen, Søren Krogsgaard; Hartmann, Bolette; Chen, Yi-Chun; Jonsson, Anna E; Kabakci, Hasan; Thaman, Swaraj; Grarup, Niels; Have, Christian T; Pallo, Lindsay P; Faerch, Kristine; Gjesing, Anette P; Nawaz, Sameena; Cheeseman, Jane; Neville, Matthew J; Pedersen, Oluf; Walker, Mark; Sun, Han; Jennison, Christopher; Hattersley, Andrew T; Rehfeld, Jens F; Holman, Rury R; Verchere, Bruce C; Hansen, Torben; Karpe, Fredrik; Holst, Jens J; Rosenkilde, Mette M; Jones, Angus G; Ristow, Michael; McCarthy, Mark I; Pearson, Ewan R; Stoffel, Markus; Gloyn, Anna L

Mitochondrial movement in pancreatic alpha cells requires Miro2 and is regulated by glucose.

胰岛α细胞中的线粒体运动需要Miro2,并受葡萄糖调节。

Ekstrand Maia H, Nawaz Sameena, Clark Anne, Hastoy Benoit, Knudsen Jakob G

Comparison of "Continuous" and "End-ischemic" Approaches of Oxygenated Hypothermic Machine Perfusion for Pancreas Preservation

氧合低温机械灌注在胰腺保护中的“连续”与“缺血末期”方法的比较

Elzawahry, Mohamed Aly Mohamed Elshafei; Fallon, John; Hastoy, Benoit; Lo Faro, Maria Letizia; Nawaz, Sameena; Branchereau, Julien; Clark, Anne; Friend, Peter; Ploeg, Rutger; Hunter, James

Ticking Differently: Elucidating Sexual Dimorphism in Human Aging through Metabolomics, Proteomics and Genomics

不同的衰老机制:通过代谢组学、蛋白质组学和基因组学阐明人类衰老中的性别二态性

Xiao, Sihao; Kaushik, Pallavi; Du, Gaoyu; Liu, Bowen; Hosawi, Salman B; Hastoy, Benoit; Argentieri, M Austin; Winchester, Laura M; Nevado-Holgado, Alejo J; Kaddurah-Daouk, Rima; Amin, Najaf; van Duijn, Cornelia

Electrophysiological Characterization of Inducible Pluripotent Stem Cell-Derived Human β-Like Cells and an SLC30A8 Disease Model.

诱导多能干细胞衍生的人类β样细胞的电生理特性及SLC30A8疾病模型

Jaffredo Manon, Krentz Nicole A J, Champon Benoite, Duff Claire E, Nawaz Sameena, Beer Nicola, Honore Christian, Clark Anne, Rorsman Patrik, Lang Jochen, Gloyn Anna L, Raoux Matthieu, Hastoy Benoit

Roles for the long non-coding RNA Pax6os1/ PAX6-AS1 in pancreatic beta cell function

长链非编码RNA Pax6os1/PAX6-AS1在胰岛β细胞功能中的作用

Livia Lopez-Noriega ,Rebecca Callingham ,Aida Martinez-Sánchez ,Sameena Nawaz ,Grazia Pizza ,Nejc Haberman ,Nevena Cvetesic ,Marie-Sophie Nguyen-Tu ,Boris Lenhard ,Piero Marchetti ,Lorenzo Piemonti ,Eelco de Koning ,A M James Shapiro ,Paul R Johnson ,Isabelle Leclerc ,Benoit Hastoy ,Benoit R Gauthier ,Timothy J Pullen ,Guy A Rutter

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion

对STARD10基因座的染色质三维相互作用分析揭示了FCHSD2是胰岛素分泌的调节因子

Hu, Ming; Cebola, Inês; Carrat, Gaelle; Jiang, Shuying; Nawaz, Sameena; Khamis, Amna; Canouil, Mickaël; Froguel, Philippe; Schulte, Anke; Solimena, Michele; Ibberson, Mark; Marchetti, Piero; Cardenas-Diaz, Fabian L; Gadue, Paul J; Hastoy, Benoit; Almeida-Souza, Leonardo; McMahon, Harvey; Rutter, Guy A

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

作者更正:超分辨率显微镜兼容的荧光探针揭示内源性胰高血糖素样肽-1受体的分布和动态变化

Ast, Julia; Arvaniti, Anastasia; Fine, Nicholas H F; Nasteska, Daniela; Ashford, Fiona B; Stamataki, Zania; Koszegi, Zsombor; Bacon, Andrea; Jones, Ben J; Lucey, Maria A; Sasaki, Shugo; Brierley, Daniel I; Hastoy, Benoit; Tomas, Alejandra; D'Agostino, Giuseppe; Reimann, Frank; Lynn, Francis C; Reissaus, Christopher A; Linnemann, Amelia K; D'Este, Elisa; Calebiro, Davide; Trapp, Stefan; Johnsson, Kai; Podewin, Tom; Broichhagen, Johannes; Hodson, David J

AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity

AP2σ突变会损害钙敏感受体的运输和信号传导,并显示出一种通过内体途径空间定向G蛋白选择性的机制

Gorvin, Caroline M; Rogers, Angela; Hastoy, Benoit; Tarasov, Andrei I; Frost, Morten; Sposini, Silvia; Inoue, Asuka; Whyte, Michael P; Rorsman, Patrik; Hanyaloglu, Aylin C; Breitwieser, Gerda E; Thakker, Rajesh V

Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion

糖尿病基因SOX4表达增加通过损害融合孔扩张来减少胰岛素分泌

Collins, Stephan C; Do, Hyun Woong; Hastoy, Benoit; Hugill, Alison; Adam, Julie; Chibalina, Margarita V; Galvanovskis, Juris; Godazgar, Mahdieh; Lee, Sheena; Goldsworthy, Michelle; Salehi, Albert; Tarasov, Andrei I; Rosengren, Anders H; Cox, Roger; Rorsman, Patrik