日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Effect of Advancing Age and Intraocular Pressure Injury on Retinal Ganglion Cell Function and Synaptic Connectivity

年龄增长和眼内压损伤对视网膜神经节细胞功能和突触连接的影响

Chrysostomou, Vicki; Ellis, Sevannah; Fry, Lewis E; Hatch, Robert J; Fahy, Eamonn T; Bell, Katharina C; Trounce, Ian A; van Wijngaarden, Peter; Petrou, Steve; Crowston, Jonathan G

Carbogen-Induced Respiratory Acidosis Blocks Experimental Seizures by a Direct and Specific Inhibition of Na(V)1.2 Channels in the Axon Initial Segment of Pyramidal Neurons

碳氧混合气诱导的呼吸性酸中毒通过直接特异性抑制锥体神经元轴突起始段的Na(V)1.2通道来阻断实验性癫痫发作

Hatch, Robert J; Berecki, Géza; Jancovski, Nikola; Li, Melody; Rollo, Ben; Jafar-Nejad, Paymaan; Rigo, Frank; Kaila, Kai; Reid, Christopher A; Petrou, Steven

The novel persistent sodium current inhibitor PRAX-562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers.

新型持续性钠电流抑制剂 PRAX-562 具有强效抗惊厥活性,与标准钠通道阻滞剂相比,其保护指数有所提高

Kahlig Kristopher M, Scott Liam, Hatch Robert J, Griffin Andrew, Martinez Botella Gabriel, Hughes Zoë A, Wittmann Marion