Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice.
将 RNAi 表达构建体通过 AAV 脑脊液内递送至非人灵长类动物和小鼠后，引起背根神经节毒性
期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.11.029
Hawley Zachary C E, Pardo Ingrid D, Cao Shaolong, Zavodszky Maria I, Casey Fergal, Ferber Kyle, Luo Yi, Hana Sam, Chen Shukkwan K, Doherty Jessica, Costa Raquel, Cullen Patrick, Liu Yuqing, Carlile Thomas M, Chowdhury Twinkle, Doyle Benjamin, Clarner Pete, Mangaudis Kevin, Guilmette Edward, Bourque Shawn, Koske David, Nadella Murali V P, Trapa Patrick, Hawes Michael L, Raitcheva Denitza, Lo Shih-Ching
