日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The peptide genomic therapy increases antibacterial immunity and survival in sepsis by reprograming the gene orthologs of human immunodeficiencies in the spleen and lungs

肽基因组疗法通过重编程脾脏和肺部人类免疫缺陷的同源基因,提高脓毒症患者的抗菌免疫力和存活率。

Qiao, Huan; Zienkiewicz, Jozef; Liu, Yan; Hawiger, Jacek

Advances and transgressions of nuclear transport checkpoint inhibitors

核转运检查点抑制剂的进展与突破

Hawiger, Jacek

Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18

靶向IL-17A可减轻IL-18诱导的新生儿败血症死亡率

Wynn, James Lawrence; Wilson, Chris S; Hawiger, Jacek; Scumpia, Philip O; Marshall, Andrew F; Liu, Jin-Hua; Zharkikh, Irina; Wong, Hector R; Lahni, Patrick; Benjamin, John T; Plosa, Erin J; Weitkamp, Jörn-Hendrik; Sherwood, Edward R; Moldawer, Lyle L; Ungaro, Ricardo; Baker, Henry V; Lopez, M Cecilia; McElroy, Steven J; Colliou, Natacha; Mohamadzadeh, Mansour; Moore, Daniel Jensen

Interleukin 2 Activates Brain Microvascular Endothelial Cells Resulting in Destabilization of Adherens Junctions.

白细胞介素 2 激活脑微血管内皮细胞,导致粘附连接不稳定

Wylezinski Lukasz S, Hawiger Jacek

The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation.

细菌内毒素引起的“基因组风暴”可通过核转运调节剂来缓解,该调节剂可减轻局部和全身炎症

DiGiandomenico Antonio, Veach Ruth Ann, Zienkiewicz Jozef, Moore Daniel J, Wylezinski Lukasz S, Hutchens Martha A, Hawiger Jacek

Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver

核转运调节可降低高胆固醇血症、动脉粥样硬化和脂肪肝

Liu, Yan; Major, Amy S; Zienkiewicz, Jozef; Gabriel, Curtis L; Veach, Ruth Ann; Moore, Daniel J; Collins, Robert D; Hawiger, Jacek

The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling.

先天免疫接头蛋白SARM转移到细胞核内,稳定核纤层,防止DNA在促凋亡信号的作用下发生断裂

Sethman Chad R, Hawiger Jacek

Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3

细胞穿透性细胞因子信号抑制因子3的抗降解突变体的延长抗炎作用

Fletcher, Tynetta C; DiGiandomenico, Antonio; Hawiger, Jacek

Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor

通过细胞内肽递送核输入抑制剂抑制急性肺部炎症

Liu, Danya; Zienkiewicz, Jozef; DiGiandomenico, Antonio; Hawiger, Jacek

Intracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling

胞内递送靶向IFN-γ信号通路的细胞穿透性SOCS1

DiGiandomenico, Antonio; Wylezinski, Lukasz S; Hawiger, Jacek