日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

2-Hydroxyestradiol regulates extracellular matrix deposition through estrogen receptor beta activation in airway smooth muscle cells.

2-羟基雌二醇通过激活气道平滑肌细胞中的雌激素受体β来调节细胞外基质沉积。

期刊:Molecular and Cellular Endocrinology
影响因子:3.6
doi:10.1016/j.mce.2026.112753
Kumar Ashish, Reza Mohammad Irshad, Banerjee Anurag, Ambhore Nilesh Sudhakar, Balraj Premanand, Layek Buddhadev, Thompson Michael A, Hawse John R, Pabelick Christina M, Prakash Y S, Sathish Venkatachalem
细胞生物学
发表日期：2026
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Lestaurtinib's antineoplastic activity converges on JAK/STAT signaling to inhibit treatment naïve and therapy resistant forms ovarian cancer.

Lestaurtinib 的抗肿瘤活性集中于 JAK/STAT 信号通路，可抑制未经治疗和对治疗耐药的卵巢癌

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-025-00947-0
Rodman Esther P B, Emch Michael J, Hou Xiaonan, Bajaj Archit, Pearson Nicole A, John August J, Ortiz Yamillie, Bass Adam D, Singh Saloni, Baldassarre Gustavo, Kaufmann Scott H, Weroha S John, Hawse John R
信号转导
肿瘤
卵巢癌
JAK/STAT
肿瘤免疫
发表日期：2025
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Anti-Neoplastic Activity of Estrogen Receptor Beta in Chemoresistant Triple-Negative Breast Cancer.

雌激素受体β在化疗耐药性三阴性乳腺癌中的抗肿瘤活性

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17132132
Wang Xiyin, Emch Michael J, Goetz Matthew P, Hawse John R
肿瘤
乳腺癌
发表日期：2025
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Unbiased CRISPR Synthetic Lethal Screening for Genetic Vulnerabilities in Succinate Dehydrogenase (SDH)-loss Model of Paraganglioma

利用无偏倚的 CRISPR 合成致死筛选技术，在副神经节瘤琥珀酸脱氢酶 (SDH) 缺失模型中寻找遗传脆弱性

期刊:
影响因子:
doi:10.1101/2025.08.26.672429
Al Khazal, Fatimah J; Emch, Michael J; de Araujo Correia, Cristina M; Favier, Judith; Hawse, John R; Maher, L James
发表日期：2025
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Lestaurtinib's antineoplastic activity converges on JAK/STAT signaling to inhibit advanced forms of therapy resistant ovarian cancer

Lestaurtinib 的抗肿瘤活性主要通过抑制 JAK/STAT 信号通路来抑制晚期耐药性卵巢癌。

期刊:
影响因子:
doi:10.1101/2024.06.06.597753
Rodman, Esther P B; Emch, Michael J; Hou, Xiaonan; Bajaj, Archit; Pearson, Nicole A; John, August J; Ortiz, Yamillie; Bass, Adam D; Singh, Saloni; Baldassarre, Gustavo; Kaufmann, Scott H; Weroha, S John; Hawse, John R
肿瘤
JAK/STAT
卵巢癌
肿瘤免疫
信号转导
发表日期：2024
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A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer

TGF-β/KLF10信号通路通过调控萎缩相关基因诱导胰腺癌肌肉萎缩

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2215095120
Dasgupta, Aneesha; Gibbard, Daniel F; Schmitt, Rebecca E; Arneson-Wissink, Paige C; Ducharme, Alexandra M; Bruinsma, Elizabeth S; Hawse, John R; Jatoi, Aminah; Doles, Jason D
胰腺癌
肿瘤
TGF-β
肿瘤免疫
信号转导
发表日期：2023
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Estrogen-regulated miRs in bone enhance osteoblast differentiation and matrix mineralization

雌激素调控的骨骼miRNA促进成骨细胞分化和基质矿化

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2023.05.026
Emch, Michael J; Wicik, Zofia; Aspros, Kirsten G M; Vukajlovic, Tanja; Pitel, Kevin S; Narum, Anders K; Weivoda, Megan M; Tang, Xiaojia; Kalari, Krishna R; Turner, Russell T; Iwaniec, Urszula T; Monroe, David G; Subramaniam, Malayannan; Hawse, John R
信号转导
细胞生物学
miRNA
免疫/内分泌
发表日期：2023
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Disruption of estrogen receptor beta's DNA binding domain impairs its tumor suppressive effects in triple negative breast cancer

雌激素受体β DNA结合域的破坏会削弱其在三阴性乳腺癌中的肿瘤抑制作用

期刊:Frontiers in Medicine
影响因子:3
doi:10.3389/fmed.2023.1047166
Aspros, Kirsten G M; Emch, Michael J; Wang, Xiyin; Subramaniam, Malayannan; Hinkle, Megan L; Rodman, Esther P B; Goetz, Matthew P; Hawse, John R
肿瘤
肿瘤免疫
信号转导
乳腺癌
免疫/内分泌
发表日期：2023
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Adenosine A(2A) receptor blockade prevents cisplatin-induced impairments in neurogenesis and cognitive function

腺苷A(2A)受体阻断可预防顺铂引起的神经发生和认知功能障碍

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2206415119
Oliveros, Alfredo; Yoo, Ki Hyun; Rashid, Mohammad Abdur; Corujo-Ramirez, Ana; Hur, Benjamin; Sung, Jaeyun; Liu, Yuanhang; Hawse, John R; Choi, Doo-Sup; Boison, Detlev; Jang, Mi-Hyeon
信号转导
神经科学
发表日期：2022
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Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer

雌激素受体β通过重新利用EZH2来抑制三阴性乳腺癌中的致癌NFκB/p65信号通路

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-022-00387-0
Aspros, Kirsten G M; Carter, Jodi M; Hoskin, Tanya L; Suman, Vera J; Subramaniam, Malayannan; Emch, Michael J; Ye, Zhenqing; Sun, Zhifu; Sinnwell, Jason P; Thompson, Kevin J; Tang, Xiaojia; Rodman, Esther P B; Wang, Xiyin; Nelson, Adam W; Chernukhin, Igor; Hamdan, Feda H; Bruinsma, Elizabeth S; Carroll, Jason S; Fernandez-Zapico, Martin E; Johnsen, Steven A; Kalari, Krishna R; Huang, Haojie; Leon-Ferre, Roberto A; Couch, Fergus J; Ingle, James N; Goetz, Matthew P; Hawse, John R
肿瘤
肿瘤免疫
信号转导
乳腺癌
EZH2
免疫/内分泌
发表日期：2022
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