日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System

治疗慢性疼痛和增强受损的下行去甲肾上腺素能抑制系统的策略

Hayashida, Ken-Ichiro; Obata, Hideaki

Peripheral nerve injury in rats induces alternations in choice behavior associated with food reinforcement

大鼠周围神经损伤会导致与食物强化相关的选择行为发生改变。

Hayashida, Ken-Ichiro; Eisenach, James C; Kawatani, Masahito; Martin, Thomas J

Disruption of Spinal Noradrenergic Activation Delays Recovery of Acute Incision-Induced Hypersensitivity and Increases Spinal Glial Activation in the Rat

脊髓去甲肾上腺素能激活的破坏会延缓大鼠急性切口诱发的超敏反应的恢复,并增加脊髓胶质细胞的激活。

Arora, Vipin; Morado-Urbina, Carlos Eduardo; Aschenbrenner, Carol A; Hayashida, Ken-Ichiro; Wang, FuZhou; Martin, Thomas J; Eisenach, James C; Peters, Christopher M

Individual differences in acute pain-induced endogenous analgesia predict time to resolution of postoperative pain in the rat

大鼠急性疼痛诱导的内源性镇痛的个体差异可预测术后疼痛消退时间

Peters, Christopher M; Hayashida, Ken-Ichiro; Suto, Takashi; Houle, Timothy T; Aschenbrenner, Carol A; Martin, Thomas J; Eisenach, James C

Nerve injury induces a new profile of tactile and mechanical nociceptor input from undamaged peripheral afferents

神经损伤会诱发来自未受损外周传入神经的触觉和机械性伤害感受器输入的新模式。

Boada, M Danilo; Gutierrez, Silvia; Aschenbrenner, Carol A; Houle, Timothy T; Hayashida, Ken-Ichiro; Ririe, Douglas G; Eisenach, James C

Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms

加巴喷丁通过星形胶质细胞谷氨酸转运体依赖性机制增加蓝斑核的细胞外谷氨酸水平。

Suto, Takashi; Severino, Amie L; Eisenach, James C; Hayashida, Ken-ichiro

Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury

丙戊酸盐可预防脊髓谷氨酸失调,并减轻大鼠周围神经损伤后的超敏反应。

Yoshizumi, Masaru; Eisenach, James C; Hayashida, Ken-ichiro

Oxytocin inhibits the membrane depolarization-induced increase in intracellular calcium in capsaicin sensitive sensory neurons: a peripheral mechanism of analgesic action

催产素抑制辣椒素敏感感觉神经元中膜去极化诱导的细胞内钙离子浓度升高:一种外周镇痛机制

Hobo, Shotaro; Hayashida, Ken-ichiro; Eisenach, James C

Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat

脊髓注射昂丹司琼对大鼠脊神经结扎后的热痛觉过敏和机械痛觉过敏缺乏镇痛效果

Peters, Christopher M; Hayashida, Ken-ichiro; Ewan, Eric E; Nakajima, Kunie; Obata, Hideaki; Xu, Qinghao; Yaksh, Tony L; Eisenach, James C

Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats.

脑源性神经生长因子可诱导脊髓去甲肾上腺素能纤维萌芽,并增强大鼠神经损伤后可乐定镇痛作用

Hayashida Ken-Ichiro, Clayton Bridgette A, Johnson James E, Eisenach James C