日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhancing the Antipsychotic Effect of Risperidone by Increasing Its Binding Affinity to Serotonin Receptor via Picric Acid: A Molecular Dynamics Simulation

通过苦味酸提高利培酮与5-羟色胺受体的结合亲和力,从而增强其抗精神病作用:分子动力学模拟

Alhomrani, Majid; Alsanie, Walaa F; Alamri, Abdulhakeem S; Alyami, Hussain; Habeeballah, Hamza; Alkhatabi, Heba A; Felimban, Raed I; Haynes, John M; Shakya, Sonam; Raafat, Bassem M; Refat, Moamen S; Gaber, Ahmed

Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson's disease

抑制β-catenin依赖的WNT信号通路可上调转录抑制因子NR0B1,并下调人胚胎干细胞来源的多巴胺能神经元中A9表型的标志物:对帕金森病的影响

Haynes, John M; Sibuea, Shanti M; Aguiar, Alita A; Li, Fangwei; Ho, Joan K; Pouton, Colin W

PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

神经干细胞中PI3K的激活会驱动肿瘤发生,而靶向cAMP反应元件结合蛋白可以缓解这一过程。

Daniel, Paul M; Filiz, Gulay; Brown, Daniel V; Christie, Michael; Waring, Paul M; Zhang, Yi; Haynes, John M; Pouton, Colin; Flanagan, Dustin; Vincan, Elizabeth; Johns, Terrance G; Montgomery, Karen; Phillips, Wayne A; Mantamadiotis, Theo

Facile One-step Micropatterning Using Photodegradable Methacrylated Gelatin Hydrogels for Improved Cardiomyocyte Organization and Alignment.

利用光降解甲基丙烯酸明胶水凝胶进行简便的一步微图案化,以改善心肌细胞的组织和排列

Tsang Kelly M C, Annabi Nasim, Ercole Francesca, Zhou Kun, Karst Daniel, Li Fanyi, Haynes John M, Evans Richard A, Thissen Helmut, Khademhosseini Ali, Forsythe John S

Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines.

对源自晚发型亨廷顿病人类胚胎干细胞系的脑前神经元进行表征

Niclis Jonathan C, Pinar Anita, Haynes John M, Alsanie Walaa, Jenny Robert, Dottori Mirella, Cram David S

DNA-dependent protein kinase is a context dependent regulator of Lmx1a and midbrain specification

DNA依赖性蛋白激酶是Lmx1a和中脑分化的一种上下文依赖性调节因子。

Hunt, Cameron P; Fabb, Stewart A; Pouton, Colin W; Haynes, John M

The residual nonadrenergic contractile response to nerve stimulation of the mouse prostate is mediated by acetylcholine but not ATP in a comparison with the mouse vas deferens

与小鼠输精管相比,小鼠前列腺对神经刺激的残余非肾上腺素能收缩反应是由乙酰胆碱介导的,而不是由ATP介导的。

White, Carl W; Short, Jennifer L; Haynes, John M; Evans, Richard J; Ventura, Sabatino