Genome-Wide CRISPR Screen Identifies Phospholipid Scramblase 3 as the Biological Target of Mitoprotective Drug SS-31.
全基因组 CRISPR 筛选鉴定出磷脂扰乱酶 3 为线粒体保护药物 SS-31 的生物靶点
期刊:Journal of the American Society of Nephrology
影响因子:9.4
doi:10.1681/ASN.0000000000000338
Silvaroli Josie A, Bisunke Bijay, Kim Ji Young, Stayton Amanda, Jayne Laura A, Martinez Shirely A, Nguyen Christopher, Patel Prisha S, Vanichapol Thitinee, Verma Vivek, Akhter Juheb, Bolisetty Subhashini, Madhavan Sethu M, Kuscu Cem, Coss Christopher C, Zepeda-Orozco Diana, Parikh Samir V, Satoskar Anjali A, Davidson Alan J, Eason James D, Szeto Hazel H, Pabla Navjot S, Bajwa Amandeep