日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The development of novel glucocorticoid receptor antagonists: From rational chemical design to therapeutic efficacy in metabolic disease models

新型糖皮质激素受体拮抗剂的开发:从合理的化学设计到代谢疾病模型中的治疗效果

Jan Kroon, Eva M G Viho, Max Gentenaar, Lisa L Koorneef, Cees van Kooten, Patrick C N Rensen, Sander Kooijman, Hazel Hunt, Onno C Meijer

An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model

用于量化三维共培养模型中免疫-肿瘤相互作用的综合框架

Gheed Al-Hity ,FengWei Yang ,Eduard Campillo-Funollet ,Andrew E Greenstein ,Hazel Hunt ,Myrthe Mampay ,Haya Intabli ,Marta Falcinelli ,Anotida Madzvamuse ,Chandrasekhar Venkataraman ,Melanie S Flint

Glucocorticoid receptors signaling impairment potentiates amyloid-β oligomers-induced pathology in an acute model of Alzheimer's disease

糖皮质激素受体信号传导障碍增强了阿尔茨海默病急性模型中淀粉样β寡聚体诱发的病理

Geoffrey Canet, Fanny Pineau, Charleine Zussy, Célia Hernandez, Hazel Hunt, Nathalie Chevallier, Véronique Perrier, Joan Torrent, Joseph K Belanoff, Onno C Meijer, Catherine Desrumaux, Laurent Givalois

The selective glucocorticoid receptor antagonist CORT125281 has tissue-specific activity

选择性糖皮质激素受体拮抗剂 CORT125281 具有组织特异性活性

Lisa L Koorneef, Jan Kroon, Eva M G Viho, Lucas F Wahl, Kim M L Heckmans, Marloes M A R van Dorst, Menno Hoekstra, René Houtman, Hazel Hunt, Onno C Meijer

Glucocorticoid antagonism limits adiposity rebound and glucose intolerance in young male rats following the cessation of daily exercise and caloric restriction

糖皮质激素拮抗作用可限制年轻雄性大鼠在停止日常运动和热量限制后肥胖反弹和葡萄糖不耐受

Trevor Teich, Emily C Dunford, Deanna P Porras, Jacklyn A Pivovarov, Jacqueline L Beaudry, Hazel Hunt, Joseph K Belanoff, Michael C Riddell

Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats

选择性和非选择性糖皮质激素受体Ⅱ拮抗剂对幼年大鼠速发型糖尿病的影响

Jacqueline L Beaudry, Emily C Dunford, Trevor Teich, Dessi Zaharieva, Hazel Hunt, Joseph K Belanoff, Michael C Riddell