日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule

使用异双功能降解分子靶向急性髓系白血病中的谱系特异性 PI3Kɣ-Akt 信号传导模块

Lois M Kelly #, Justine C Rutter #, Kevin H Lin #, Frank Ling, Matthieu Duchmann, Emmanuelle Latour, Nadia Arang, Hélène Pasquer, Duong Ho Nhat, Juliette Charles, Shane T Killarney, Hazel X Ang, Federica Namor, Cécile Culeux, Bérangère Lombard, Damarys Loew, Danielle L Swaney, Nevan J Krogan, Luc Br

A versatile method for the identification of senolytic compounds

一种鉴定抗衰老化合物的通用方法

Chiara Annunziata, Francesca Castoldi, Schlegel Jan, Hazel X Ang, Mina Ristovska, Stefania Melini, Robert Welch, Christian G Riedel, Federico Pietrocola

CBF-Beta Mitigates PI3K-Alpha-Specific Inhibitor Killing through PIM1 in PIK3CA-Mutant Gastric Cancer

CBF-Beta 通过 PIM1 减轻 PIK3CA 突变型胃癌中 PI3K-Alpha 特异性抑制剂的杀伤作用

Lyla J Stanland, Hazel X Ang, Jacob P Hoj, Yunqiang Chu, Patrick Tan, Kris C Wood, Micah A Luftig

Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13

EGFR 和 CDK12/13 协同调节三阴性乳腺癌中的偶联癌蛋白合成和稳定性

Hazel X Ang, Natalia Sutiman, Xinyue L Deng, Annie Liu, Christian G Cerda-Smith, Haley M Hutchinson, Holly Kim, Luke C Bartelt, Qiang Chen, Alejandro Barrera, Jiaxing Lin, Zhecheng Sheng, Ian C McDowell, Timothy E Reddy, Christopher V Nicchitta, Kris C Wood

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia

P2RY2-AKT 激活是 XPO1 抑制在急性髓系白血病中可治疗的结果

Kevin H Lin #, Justine C Rutter #, Abigail Xie, Shane T Killarney, Camille Vaganay, Chaima Benaksas, Frank Ling, Gaetano Sodaro, Paul-Arthur Meslin, Christopher F Bassil, Nina Fenouille, Jacob Hoj, Rachel Washart, Hazel X Ang, Christian Cerda-Smith, Paul Chaintreuil, Arnaud Jacquel, Patrick Auberger